Tsukuba Gakuen Hospital

Reconstruction with megaprosthesis for recurrent nonunion of an atypical periprosthetic femoral fracture in an elderly patient

Yuto NISHIURA, Tomohiro Yoshizawa, Tomofumi Nishino, Toshiki Muramatsu et autres

An 89-year-old woman who had previously undergone cementless hemiarthroplasty for a left femoral neck fracture sustained a Vancouver type C periprosthetic femoral fracture with radiographic features suggestive of an atypical femoral fracture. Both attempts at internal fixation resulted in nonunion accompanied by …

jp (code pays fourni par la source)

Sexual function concerns and attitudes toward discussing them with psychiatrists among psychiatric outpatients in Japan: a cross-sectional study

Haruhiko Midorikawa, Kosuke Kojo, Takaaki Matsuda, Takazo Tanaka et autres

BACKGROUND: Sexual dysfunction, defined as persistent difficulties in sexual desire, arousal, or orgasm, affects treatment adherence to psychotropic medication and quality of life in people with mental disorders, yet patients rarely disclose such concerns to clinicians. Understanding patient-perceived barriers to disclosure is …

jp (code pays fourni par la source)

Balloon-occluded Alternative Infusion of Fragmented Gelatin Particles of TACE for Hepatocellular Carcinoma Refractory to Atezolizumab-Bevacizumab

Naoyuki Hasegawa, Sodai Hoshiai, TAKESHI YAMADA, NOBUYUKI TAKAHASHI et autres

BACKGROUND/AIM: This study aimed to verify the efficacy and safety of balloon-occluded alternative infusion of cisplatin solution and gelatin particles of transarterial chemoembolization (BOAI-TACE) for hepatocellular carcinoma (HCC) refractory or intolerant to atezolizumab plus bevacizumab combination therapy. PATIENTS AND METHODS: This prospective, …

jp (code pays fourni par la source)

Real-world clinical outcomes of immune checkpoint inhibitors beyond 2 Years in patients with non-small cell lung cancer: A multicenter retrospective study

Tomoyuki Ogata, Hiroaki Satoh, Masaharu Inagaki, Kunihiko Miyazaki et autres

Background Immune checkpoint inhibitors (ICIs) are the standard of care for advanced non-small cell lung cancer (NSCLC). Accumulating clinical evidence, along with increasing consideration of safety and medical costs, has led to growing discussion regarding treatment discontinuation at around 2 years in …

jp (code pays fourni par la source)

Long‐Term Outcomes of Sofosbuvir/Velpatasvir Treatment for Hepatitis C Virus‐Related Decompensated Cirrhosis: A Retrospective Multicenter Cohort Study

Satoru Kakizaki, Tadashi Ikegami, Takeshi Hatanaka, Y. Suzuki et autres

BACKGROUND: Sofosbuvir/velpatasvir (SOF/VEL) treatment for hepatitis C virus (HCV)-related decompensated cirrhosis has been shown to achieve a high sustained virologic response (SVR) rate and to improve liver function. However, limited data are available regarding the association between improvements in liver function and …

jp (code pays fourni par la source)

Back Muscle Strength Is Associated with Self-Reported Morning-Erection Frequency in Apparently Healthy Japanese Male University Students: A Cross-Sectional Study

Yoshiaki Endo, Takazo Tanaka, Kosuke Kojo, Chiaki Matsumoto et autres

Background/Objectives: Morning erections provide an intercourse-independent indicator of nocturnal erectile physiology. We aimed to examine whether body mass index (BMI) and muscle strength are associated with morning-erection frequency in apparently healthy Japanese male university students. Methods: This cross-sectional study analyzed 125 men …

jp (code pays fourni par la source)

Urinary isoflavone concentrations and semen parameters of Japanese men seeking fertility treatment

Shoko Konishi, Yuki Mizuno, K. Yamasaki, Masahiro Uchida et autres

This study aimed to analyze the associations between urinary genistein, daidzein, and equol concentrations and semen parameters in Japanese men exposed to high levels of isoflavone in their diet. Between September 2020 and March 2021, men seeking fertility treatment (n = 157) …

jp (code pays fourni par la source)

Editorial Comment on “Investigating the Effect of Synbiotic and SperiGen Supplementations on Spermatogram in Idiopathic Oligoasthenoteratozoospermia: A Double‐Blinded Randomized Clinical Trial”

Kosuke Kojo, K. Yamasaki, Tatsuya Takayama

The authors declare no conflicts of interest. No new data were generated or analyzed in support of this research. All data discussed in this article are available in the cited references.

jp (code pays fourni par la source)

Step‐by‐step: A traction‐based fenestration method for vasoepididymostomy

Kosuke Kojo, Masahiro Uchida, K. Yamasaki, Jaejeong Kim et autres

I G U R E 1 (a) Step 1. Two double-armed sutures are placed through the exposed epididymal tubule (arrow), with a separate traction suture passed between them.(b) Step 2. While gently lifting the traction suture, ophthalmic scissors are used to excise …

jp (code pays fourni par la source)

Correction: A case of autosomal dominant polycystic kidney disease with systemic lupus erythematosus developing after SARS‑CoV‑2 vaccination

Joichi Usui, Tatsuya Shimizu, Soichiro Nomura, Toshiaki Usui et autres

jp (code pays fourni par la source)

Comparison of R2 value estimations using spin echo-multi echo and T2 mapping techniques for polymer gel dosimetry in radiotherapy

Norikazu Koori, Yuma Ito, Ayuna Ichiishi, Hiraku Fuse et autres

jp (code pays fourni par la source)

Real-world effectiveness of belimumab and anifrolumab in systemic lupus erythematosus: comparable trends in disease activity and glucocorticoid reduction

Ryota Sato, Masaru Shimizu, Yuya Kondo, Kazushi Maruo et autres

Despite the proven efficacy of belimumab and anifrolumab for SLE, their relative effectiveness remains uncertain owing to conflicting indirect comparison studies. We conducted a comparative effectiveness study using multicenter health records to evaluate the adjusted 12-month changes in the SLE Disease Activity …

jp (code pays fourni par la source)