Hokkaido Cancer Society

Cancer recognition and assessment through non-invasive evaluation (CRANE): A prospective clinical validation study of a multi-biomarker class multi-cancer early detection (MCED) test in Japan.

Takeaki Yamazaki, Yoshiaki Nakamura, Mitsuho Imai, Takao Fujisawa et autres

TPS10629 Background: Japan has established screening programs for gastric, colorectal, lung, cervical, and breast cancers. Blood-based multi-cancer early detection (MCED) tests utilize the measurement of shared tumor-derived biomarkers (ctDNA, proteins) and machine learning to simultaneously detect several cancer types. By complementing current …

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Five‐Year Unified Risk Prediction Model for Gastric and Esophageal Cancer Based on Nationwide Health Check‐Up Data in Japan: J‐GESS Score

Kenta Watanabe, Sho Fukuda, Dai Kubota, Nobutake Yamamichi et autres

BACKGROUND AND AIM: In Japan, gastric cancer (GC) and esophageal squamous cell carcinoma (ESCC) account for nearly all fatal upper gastrointestinal malignancies. A unified model that simultaneously predicts the incidence of these two cancers could help optimize endoscopic screening and postindex surveillance …

jp (code pays fourni par la source)

Guidelines for the management of Helicobacter pylori infection in Japan: 2024 revised edition

Hajime Isomoto, Tadashi Shimoyama, Masanori Ito, Takako Osaki et autres

BACKGROUND: The Japanese Society for Helicobacter Research (JSHR) published the fifth edition of the guidelines for the management of Helicobacter pylori (H. pylori) infection in 2024 in Japanese language. METHODS: This edition of JSHR guidelines was first developed in accordance with the …

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Short-Term Efficacy and Safety of Elobixibat for Chronic Constipation Assessed by Rectal Ultrasonography: A Retrospective Observational Study

Momoko Tsuda, Tomoyuki Onodera, Kanako Konishi, Norishige Maiya et autres

Background/Objectives: Ultrasonography (US) is a non-invasive and repeatable examination for evaluating chronic constipation. However, few studies have explored treatment decisions based on rectal US findings. To date, the efficacy and safety of elobixibat have not been evaluated using rectal US classification in …

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Combination of transvaginal ultrasound with cervical cancer screening contributes to early detection of ovarian cancer: Clinical trial

Hiromasa Fujita, Kazuhira Okamoto, Hidenori Kato, Hidemichi Watari et autres

OBJECTIVE: Early detection of ovarian cancer at stage I is important to improve patients' prognosis. The goal of this study was to examine if transvaginal ultrasound (TVU) performed at the same time as cervical cancer screening can facilitate early detection of ovarian …

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Clinical Features of Invasive Gastric Cancer Developed After Helicobacter pylori Eradication During Regular Endoscopic Surveillance

Akiko Sasaki, Junko Fujisaki, Masaaki Kobayashi, Ken Namikawa et autres

OBJECTIVES: Gastric cancer (GC) may be diagnosed after Helicobacter pylori eradication, sometimes with submucosal invasion; however, its clinical features on regular endoscopic surveillance remain unclear. This study evaluated invasive GC's characteristics after H. pylori eradication during regular endoscopic surveillance by comparing them …

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Potentially Causal Associations Between Extensive Gastric Atrophy and Esophageal Squamous Cell Carcinoma: A Nationwide Retrospective Cohort Study in Japan

Kenta Watanabe, Sho Fukuda, Dai Kubota, Nobutake Yamamichi et autres

OBJECTIVES: A potential association between esophageal squamous cell carcinoma (ESCC) and gastric atrophy (GA) has been reported. However, most published studies have used case-control designs, leading to selection bias. This study aimed to investigate the causal association between ESCC and GA using …

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A Survey on Endoscopy-Related Musculoskeletal Injuries in Japanese Endoscopists Focused on Injury Sites and Risk Factors

Shoko Ono, Sae Nakajima, Natsumi Tomita, Momoko Tsuda et autres

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Frequent Gastrointestinal Cancer Complications in Japanese Patients with Acute or Chronic Coronary Syndrome Undergoing Percutaneous Coronary Intervention

Yasuyuki Chiba, Shogo Imagawa, Yuki Takahashi, Kimitoshi Kubo et autres

Background/Objective: Gastrointestinal bleeding is a major complication of dual antiplatelet therapy (DAPT) in patients undergoing percutaneous coronary intervention (PCI). Malignancy may be detected due to gastrointestinal bleeding, necessitating critical decisions regarding treatment selection and influencing patient prognosis. Methods: This single-center, retrospective, observational …

jp (code pays fourni par la source)

Age distribution and risk factors for Barrett's esophagus by sex at health check-up settings in Japan

Sho Fukuda, Kenta Watanabe, Dai Kubota, Nobutake Yamamichi et autres

BACKGROUND: Given the high prevalence of esophageal adenocarcinoma and Barrett's esophagus (BE), a precancerous lesion, among males, it is important to understand the characteristics of BE by sex to develop an effective endoscopic surveillance program in Japan. The present study examined the …

jp (code pays fourni par la source)

Linked Color Imaging with Light-Emitting Diode Light Enhances the Visibility of Gastric Neoplasm: A Prospective, Multicenter, Comparative Trial

N. Iwai, Osamu Dohi, Takahiro Kotachi, Momoko Tsuda et autres

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Evaluating Collection Time of Intragastric Fluid During Endoscopy for Point-of-care Test-based Helicobacter pylori Polymerase Chain Reaction

Yoshiyuki Watanabe, Hiroyuki Yamamoto, Ichiro Oda, Kuniaki Torii et autres

Objective To evaluate the influence of sample collection time during esophagogastroduodenoscopy (EGD) on the accuracy of a newly approved point-of-care test (POCT)-based polymerase chain reaction kit for detecting Helicobacter pylori and clarithromycin susceptibility in gastric wash fluid. Methods Intragastric fluid was collected …

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