Combination of transvaginal ultrasound with cervical cancer screening contributes to early detection of ovarian cancer: Clinical trial
Rattachement africain : jp. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
OBJECTIVE: Early detection of ovarian cancer at stage I is important to improve patients' prognosis. The goal of this study was to examine if transvaginal ultrasound (TVU) performed at the same time as cervical cancer screening can facilitate early detection of ovarian cancer. METHODS: From 2014 to 2022, 483 269 women underwent TVU examinations during cervical cancer screening. The criteria for abnormal findings on TVU were ovarian enlargement ≥3 cm in long diameter (≥2 cm in postmenopausal women). RESULTS: Of the 483 269 women who underwent TVU, 3294 (0.68%) were selected for detailed examination. Of these women, 550 underwent surgery and 80 cases of ovarian cancer were found (positive predictive value: 2.43%). Pathologic review in 76 of these cases showed 70 cases of epithelial ovarian cancer (type I: 54 [77.1%], Type II: 16 [22.9%]) and six cases of non-epithelial malignant tumors. Clinical staging analysis showed that 81.6% (62 cases) were at stage I. Significantly more type I than type II tumors were detected at stage I (87.3% (n = 46) vs. 56.3%, P = 0.0068 (n = 9)). Notably, 95.7% (22/23) of clear cell carcinoma cases were detected at stage I. DISCUSSION: The high rate of early detection of type I ovarian cancer might be due to its slow progression. In Asia, where type I is common, the benefits of screening for ovarian cancer are particularly great. However, screening with TVU has generally been considered to have little benefit. The results of this study suggest a need for reassessment of this view.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Combination of transvaginal ultrasound with cervical cancer screening contributes to early detection of ovarian cancer: Clinical trial
- Date Crossref
- 03/11/2025
- Éditeur
- Wiley
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Japan Cancer Society pays non établi dans la noticeOrganisation à but non lucratif
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Hokkaido Cancer Society pays non établi dans la noticeOrganisation à but non lucratif
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Hokkaido University of Science pays non établi dans la noticeUniversité ou école supérieure
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Hokkaido University Department of Obstetrics and Gynecology pays non établi dans la noticeUniversité ou école supérieure
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Shin-yurigaoka General Hospital Cancer Center pays non établi dans la noticeÉtablissement de santé
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Graduate School of Medicine Department of Obstetrics and Gynecology pays non établi dans la noticeUniversité ou école supérieure
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Ozawa Women's General Clinic Senndai Miyagiken Japan pays non établi dans la noticeÉtablissement de santé
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Shin‐Yurigaoka General Hospital Kawasaki Kanagawaken Japan Cancer Center pays non établi dans la noticeÉtablissement de santé
Japan Cancer Society, Hokkaido Cancer Society et Hokkaido University of Science, avec 5 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.