EcoSynthetix (United States)

Assessing the Lower Face: Lips, Chin, and Jawline

Kavita Mariwalla, Sabrina Guillen Fabi, Daniel Belkin, José Raúl Montes et autres

BACKGROUND: The lower face, including the lips, chin, and jawline, plays a defining role in facial proportion and expression. Aging of this region involves a complex interplay of skeletal remodeling, soft tissue descent, and muscle hyperactivity, which manifest differently across ethnic groups …

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Current Standards of Facial Assessment and Opportunities for Improvement

Kavita Mariwalla, Sabrina Guillen Fabi, Daniel Belkin, José Raúl Montes et autres

BACKGROUND: Evolving patterns of global migration, cultural exchange, and social media exposure have diversified perceptions of facial attractiveness and reshaped patient expectations for aesthetic treatment. Conventional assessment tools based on Western-centric beauty ideals no longer fully capture this heterogeneity. OBJECTIVE: To identify …

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Assessing the Midface: Nose and Cheeks

Kavita Mariwalla, Sabrina Guillen Fabi, Daniel Belkin, José Raúl Montes et autres

BACKGROUND: The midface, encompassing the nose, nasolabial folds, and cheeks, plays a central role in facial harmony and perceived youthfulness. Midface aging involves skeletal remodeling, fat compartment atrophy, and ligamentous laxity, which vary across ethnic and cultural groups. OBJECTIVE: To describe the …

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Putting it all Together: Assessing the Whole Face in the Context of the Whole Patient

Kavita Mariwalla, Sabrina Guillen Fabi, Daniel Belkin, José Raúl Montes et autres

BACKGROUND: Facial rejuvenation is most effective when guided by a holistic, patient-centered assessment that integrates anatomical, psychological, and cultural dimensions. Emerging digital tools and structured frameworks now enable clinicians to translate this multidimensional understanding into individualized treatment plans. OBJECTIVE: To consolidate clinical …

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Assessing the Submental and Neck Region

Kavita Mariwalla, Sabrina Guillen Fabi, Daniel Belkin, José Raúl Montes et autres

BACKGROUND: The submental and neck regions significantly influence facial balance and perceived youthfulness. Growing demand for minimally invasive rejuvenation underscores the need for a deeper understanding of anatomy, aging mechanisms, and ethnic variation in these areas. OBJECTIVE: To review age-related structural changes …

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Assessing the Upper Face: Forehead and Periorbital Region

Kavita Mariwalla, Sabrina Guillen Fabi, Daniel Belkin, José Raúl Montes et autres

BACKGROUND: The upper face (forehead, brows, temples, and periorbital region) plays a central role in overall facial expression and perceived age. Treatment approaches must evolve beyond traditional Western norms to accommodate ethnic and cultural diversity in anatomy and aesthetic preferences. OBJECTIVE: To …

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Development of a multiple linear regression model for chronic nickel toxicity to Ceriodaphnia dubia: performance of bicarbonate vs. pH as toxicity modifying factors

Jordana L. Van Geest, Jennifer M Daley, Melanie J. Gallant, Kevin V. Brix et autres

Multiple linear regression models were developed to predict chronic nickel (Ni) toxicity to Ceriodaphnia dubia under an expanded range of conditions relative to published datasets. Test conditions were expanded to study Ni toxicity under very high hardness (up to 1,020 mg/L as …

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Development of a bioaccumulation model for selenium oxyanions and organoselenium in stream biota

Adrian M H de Bruyn, Cybele B Heddle, Jennifer S. Ings, Hakan Gürleyük et autres

Selenium (Se) occurs in natural surface waters as a variety of inorganic and organic chemical species, typically dominated by the oxyanions selenate and selenite. Organoselenium species, although hypothesized to be more bioavailable than oxyanions, have rarely been identified or quantified in natural …

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Neurotoxins and Combination Therapies

Lauren Gawey, Nazanin Saeedi Saedi, Amelia K. Hausauer

BACKGROUND: Facial aging involves multilevel changes, extending from the skin to deep support structures. A comprehensive treatment approach targeting the many aspects of facial dynamics and architecture is often necessary to achieve optimal correction, prevent changes before they occur, and/or help highlight …

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Commentary on “Efficacy and Safety of PrabotulinumtoxinA in Subjects With Benign Masseteric Hypertrophy: A Double-Blind, Randomized, Placebo-Controlled, Multicenter, Phase 3 Trial and Open-Label Extension Study”

Amelia K. Hausauer

*Aesthetx Plastic Surgery & Dermatology, Campbell, CA The author has indicated no significant interest with commercial supporters.

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ChatGPT as a resource for patient education in cosmetic dermatological procedures: A boon or a bane?

Melissa M. Rames, Keegan O’Hern, Jess D. Rames, Andrea A. Tooley et autres

The rapid development of artificial intelligence (AI) has prompted the medical community to consider its current and future role in health care. While the internet is now one of the most important sources of patient information.1 AI has the potential to provide …

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Recent Advances in Closed-Tube Barcoding for FastFish-ID

J. Aquiles Sanchez, John E. Rice, Lawrence J. Wangh

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