Sabrina G. Fabi

Public Discourse on Menopausal Skin Management: A YouTube Infodemiology Study of Treatment Perceptions, Sentiment, and Unmet Needs Across 43 954 Viewer Comments

Esin Diremsizoğlu, Emre Akif Arslan, Abdullah Demirbaş, Sabrina G. Fabi

ABSTRACT Background Menopausal skin changes carry significant psychosocial burden yet remain clinically under‐addressed. As women increasingly turn to digital platforms for information and peer experience, YouTube viewer comments represent an underexplored source of real‐world treatment perceptions at scale. Methods Cross‐sectional infodemiology study …

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Patient Misconceptions About Hyaluronic Acid Fillers: Experience-Based Considerations

Vince Bertucci, Deirdre Hooper, Sabrina G. Fabi, Ada Trindade de Almeida et autres

Hyaluronic acid (HA) fillers have been a mainstay of nonsurgical aesthetic treatment for the past two decades. Their safety and effectiveness are supported by a large quantity of clinical trial data and abundant real-world experience. However, there are several commonly expressed patient …

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Adipose-derived stem cell stimulation using poly-L-lactic acid injection

Raheel Arshad Zubair, Xi-Han Zhou, Sabrina G. Fabi

BACKGROUND Poly-L-lactic acid (PLLA) has been demonstrated to grow both subcutaneous adipose tissue and the dermis which may occur through stimulation of adipose-derived stem cells (ADSC). These cells maintain the integumentary system by regulating fibroblasts and immune cells, sustaining the extracellular matrix, …

Neuroendocrine Pathways in Skin Health and Homeostasis: A Systematic Review

Elizabeth Kream, Rachel Shireen Golpanian, Anna‐Marie Hosking, Monica Boen et autres

The skin is increasingly recognized as a neuroendocrine organ that continuously communicates with the nervous system, linking cutaneous biology with overall wellness. Despite growing interest in the skin-brain axis, there remains limited synthesis of interventional strategies targeting neuropeptides and neurotransmitters to improve …

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A Prospective, Placebo-Controlled, Double-Blinded, Randomized Clinical Trial Evaluating Cellular Senescence Markers, Efficacy and Tolerability of Pre and Post Care Skincare Regimen Paired with 1927 nm Diode Fractional Laser for Photodamage on the Face

Payvand Kamrani, Maya Firsowicz, Patricia Brieva, Sabrina G. Fabi

Background: The 1927 nm non-ablative fractional diode laser is used to correct photodamage. The synergistic potential of pairing it with topical antioxidants to improve results in an inclusive population has been explored. Objective: Assess the efficacy, tolerability and impact on clinical and …

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Perimenopausal Nuances in the Aging Face: A Comprehensive Perspective

Lindsey A. Pennington, Mary Claire Haver, Sabrina G. Fabi

INTRODUCTION: Perimenopause accelerates facial aging through hormonal, structural, and psychosocial changes, presenting unique challenges for facial plastic surgeons. OBJECTIVES: This viewpoint article integrates two key perspectives: (1) psychosocial impacts and patient-centered care, contributed by Dr. Mary Claire Haver, a board-certified obstetrician-gynecologist and …

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Injectables and Facelifts: Can We Coexist? A Retrospective Chart Review Assessing Injectable Treatments Preceding and Following Rhytidectomy

Bridget Myers, Maya Firsowicz, Payvand Kamrani, Steven Dayan et autres

BACKGROUND: Facelift surgery is a cornerstone of facial rejuvenation, yet it may not fully address volume loss, skin quality, or other age-related changes. Minimally invasive procedures-such as injectables and energy-based devices-are increasingly utilized before and after facelift surgery, though their impact on …

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Physicochemical Properties of Two Poly-L-Lactic Acid Injectable Implants: Potential Impact on Their Biological Properties

Luiz Eduardo Toledo Avelar, Alessandra Haddad, Sabrina G. Fabi, Michael Somenek et autres

This study evaluated the thermal properties, crystallinity, particle size, morphology, and in vivo local inflammation and persistence of two poly-L-lactic acid (PLLA) injectable implants, Sculptra® (PLLA-SCA) and GANA V® (PLLA-GA). PLLA-SCA and PLLA-GA underwent differential scanning calorimetry and X-ray powder diffraction to …

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Managing Aesthetic Needs in Prescription Medication‐Driven Rapid Weight Loss Patients: Results of an International Consensus. The Clinician Perspective

Andreas Nikolis, Michael Somenek, Steven Dayan, Hugues Cartier et autres

INTRODUCTION: The global prevalence of obesity has continued to increase at alarming rates. More recently, there has been an exponential increase in the usage of GLP1 agonists in both clinically obese patients and those seeking weight loss. As a result, there has …

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Nonfacial Use of Injectable Poly-L-lactic Acid: Safety Data From a Multicenter Observational Study in the United States

K Kay Durairaj, Ali Vafa, Shino Bay Aguilera, Sabrina G. Fabi et autres

Background: Poly-L-lactic acid (PLLA-SCA) was approved for facial aesthetic use in the USA in 2009. Nonfacial aesthetic treatment using PLLA-SCA, a collagen-stimulating injectable implant, is a frequent clinical practice, and initial studies support its safety. Objectives: The objective of this study was …

Round Table Discussion: Aesthetic Treatment Considerations for the Perimenopausal & Menopausal Patient

Sabrina G. Fabi, Maya Firsowicz, Payvand Kamrani, Zoe Draelos et autres

BACKGROUND: Menopause is a normal feature of the female aging process that commonly occurs during the 6th decade of life. During perimenopause, many negative effects begin to occur affecting the skin that are associated with decreasing production of estrogen, progesterone, and testosterone. …

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Assessing the Lower Face: Lips, Chin, and Jawline

Kavita Mariwalla, Sabrina G. Fabi, Daniel Belkin, José Raúl Montes et autres

BACKGROUND: The lower face, including the lips, chin, and jawline, plays a defining role in facial proportion and expression. Aging of this region involves a complex interplay of skeletal remodeling, soft tissue descent, and muscle hyperactivity, which manifest differently across ethnic groups …

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