International Clinical Epidemiology Network

Advocacy in action: A real-world example of nurse practitioners collaborating for formulary change

Emily Smith, Tarik Khan

ABSTRACT: Nurse practitioners (NPs) play a critical role in identifying and addressing policy barriers that affect patient care. We present a real-world example of nurse practitioner-led advocacy to improve access to hormone replacement therapy after cancer treatment. Collaboration among a practicing nurse …

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Challenges in Trials on Neonatal Sepsis- Case of ProSPoNS Trial & Role of Central Endpoint Adjudication

Anju Sinha, Dilip Raja, Kamlesh S. Mahajan, Subodh Saran Gupta et autres

Abstract Background: Despite progress in reducing Infant mortality in India, neonatal mortality decline is slower, necessitating concerted efforts to achieve Sustainable Development Goal-3. A promising strategy aiming prevention of neonatal sepsis in high-risk, vulnerable, low birth weight neonates through an innovative intervention, …

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Prognostic significance of organ failure and infected pancreatic necrosis in acute pancreatitis: An updated systematic review and meta‐analysis

Wen Mo Hu, Tianrui Hua, Yue Lun Zhang, Guo Rong Chen et autres

OBJECTIVES: In patients with acute pancreatitis (AP), minimally invasive treatment and the step-up approach have been widely used to deal with infected pancreatic necrosis (IPN) in the last decade. It is unclear whether IPN has become a less important determinant of mortality …

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A 12-month follow-up study of discharged patients with acute pancreatitis: An acute condition with prolonged sequela

Hanyue Ding, Jiayuan Dai, Jiaye Lin, Liang Gong et autres

To the Editor: Acute pancreatitis (AP) is the most common gastrointestinal condition that leads to acute hospitalization.[1] The incidence of AP has increased in recent decades, with a current global incidence of 34/100,000, probably due to a rising trend of obesity and …

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Discriminating endoscopic features of sessile serrated lesions

Wen Shi, Yuelun Zhang, Hanyue Ding, Feng Xie et autres

To the Editor: Colorectal cancer (CRC) remains a leading cause of cancer-related death worldwide.[1] In addition to the classical adenoma-to-carcinoma model of colorectal carcinogenesis, the serrated neoplastic pathway accounts for 20%–30% of CRCs. Sessile serrated lesions (SSLs), the most common premalignant serrated …

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Prevalence and correlates of childhood obesity in suburban area of Odisha: A cross sectional study

Sanghamitra Pati, Subhashisa Swain, Mohammad Akhtar Hussain, Abhimanyu Singh Chauhan

Introduction: In India obesity and overweight is increasing among urban adolescents. Both under and over nutrition is grappling the country at faster rate. Present study was an attempt to explore obesity and overweight prevalence among school going children in suburban areas of …

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Evaluating the Efficacy of a Multistrain Probiotic Supplementation for Prevention of Neonatal Sepsis in 0-2 Months Old Low Birth Weight Infants in India – The ‘ProSPoNS’ Study Protocol for a Phase III, Multicentric, Randomized, Double-Blind, Placebo-Controlled Trial.

Anju Sinha, Subodh Saran Gupta, Ramesh Poluru, Abhishek V. Raut et autres

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Molecular Diversity of Hepatitis B Virus X Gene in Central Kerala, Southern India

Ozhiparambil A Jagan, Manoj Gopi, N.S. Jayaprakash, Ramesh M Nair et autres

Introduction: Hepatitis B Virus (HBV) causes diverse clinical manifestations ranging from acute fulminant Hepatitis, Chronic Hepatitis (CHB) to liver cirrhosis and Haepatocellular Carcinoma (HCC). The HBV X gene (HBV-X) is a 154 amino acid multifunctional protein, mutates frequently and has a role …

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Draft national health policy 2015: A critical appraisal

Revising a health policy of any country is a periodic procedure dependent on the change of demographic profile, current health status of the population including epidemiological changes in disease prevalence pattern, and progress made under the earlier policies. Along with it, newer …

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Evaluating the impacts of an advanced stove intervention on traditional cooking patterns and pollutant exposures in India using Stove Use Monitors

Ajay Pillarisetti, Sankar Sambandam, Mayur Vaswani, Narendra Kumar Arora et autres

Background/Aims. Household air pollution in 2010 was responsible for ~3.5 million premature deaths and 500,000 through contributions to outdoor air pollution. 900,000 of these deaths occurred in India, where ~66% of households rely on wood, dung, or crop residues as their primary …

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What determines the adoption and continued use of advanced clean cookstoves?

Darby W. Jack, Ajay Pillarisetti, Mayur Vaswani, Kalpana Balakrishnan et autres

Background: Household air pollution is thought to be a top environmental health risk globally, and recent assessments suggest that it is the overall leading cause of DALYs in South Asia. Despite this burden of disease, solutions remain elusive. Household adoption of clean …

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Metrics to evaluate use, adoption and field performance of advanced-combustion cookstoves in a fuel-device stacking context.

Ilse Ruiz-Mercado, Omar Masera, Kirk R. Smith, Rufus David Edwards et autres

Background: Benefits from cookstove implementation can only occur when cleaner and more efficient stoves: 1) perform well in the field, 2) are used frequently, and 3) displace the older less efficient stoves. We use Stove Use Monitors (SUMs) to link laboratory performance …

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