Sanguinarine chloride inducing ferroptosis and downregulating GPX4 expression in liver cancer: An integrated in silico , in vitro and in vivo study
Wen Ouyang, Jianxin Gao, Jing Liu, Lulu Qin et autres
Ferroptosis, an iron-dependent form of regulated cell death driven by excessive lipid peroxidation, has been increasingly implicated in the development and progression of liver cancer. Despite sanguinarine chloride (SC) exhibiting antitumor activity in a number of cancer models, whether it modulates ferroptosis …
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Experimental and Therapeutic Medicine