Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma
Kimberly R. Bennett, Yann S. Vanrobaeys, Tessy Teboh, Zakiya Smith et autres
Diffuse midline glioma (DMG) is a highly aggressive pediatric brain tumor that is difficult to treat because the blood-brain-tumor barrier (BBTB) prevents most drugs from reaching the tumor. A major obstacle for understanding this tumor-vascular niche is the lack of a perfusable …
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Advanced Healthcare Materials