Accès ouvert
2026
article
OpenAlex
Kimberly R. Bennett, Yann S. Vanrobaeys, Tessy Teboh, Zakiya Smith et autres
Diffuse midline glioma (DMG) is a highly aggressive pediatric brain tumor that is difficult to treat because the blood-brain-tumor barrier (BBTB) prevents most drugs from reaching the tumor. A major obstacle for understanding this tumor-vascular niche is the lack of a perfusable …
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Accès ouvert
2026
article
OpenAlex
Kimberly R. Bennett, Monique C. Surles-Zeigler, Catherine J. Augello, Etchi Ako et autres
Introduction: Neuregulin-1 (NRG-1) is a growth factor that has been investigated for its neuroprotective properties following ischemic stroke. While NRG-1 has shown considerable promise in reducing neuronal damage, the molecular mechanisms underlying its protective effects remain unclear. This study aimed to examine …
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Accès ouvert
2024
conference-abstract
OpenAlex
Kimberly R. Bennett, Tessy Teboh, Cynthia Hajal, Roger Dale Kamm et autres
Abstract BACKGROUND Pediatric diffuse midline glioma (DMG) is a uniformly fatal brain tumor in children, with most patients surviving less than 12 months. Current treatment for DMG is limited, and outcomes for this tumor have not improved. The blood-brain-barrier (BBB) remains a …
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Accès ouvert
2021
preprint
OpenAlex
Kimberly R. Bennett, Monique C. Surles-Zeigler, Catherine J. Augello, Etchi Ako et autres
Abstract Neuregulin-1 (NRG-1) is growth factor that has been investigated for its neuroprotective properties following ischemic stroke. While NRG-1 has shown significant promise in preventing neuronal damage following stroke, the mechanisms behind its neuroprotective effects are unclear. The goal of this research …
us
(code pays fourni par la source)