Invas: an inversion-aware method for transcriptome assembly
Xuedong Wang, Fang Wang, Chenzhao Feng, Chaoyang Sun et autres
Intragenic inversions reverse sequence orientation within genes and create non-collinear splice junctions that standard transcript assemblers miss, resulting in incomplete reconstruction and biased quantification. Here we show Invas, an inversion-aware framework operating with bulk short-read sequencing data. Invas integrates whole-genome sequencing breakpoints …
hk, cn (code pays fourni par la source)
1 citation
Nature Communications