Human adenovirus protein VII inhibits type I IFN production by antagonizing viral RNA sensor RIG-I
Pei-hong Yu, Li-min Zhang, Qian Gu, Jia Liu
The genomes of human adenoviruses (HAdVs) are double-stranded DNA bound with viral nucleocapsid protein VII. During HAdV infection, host RNA polymerase can produce viral-associated RNAs (VA RNAs) that are recognized by retinoic acid-inducible gene I (RIG-I). However, it remains unclear whether and …
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Cell Reports