Accès ouvert
2026
other
OpenAlex
Sofie-Katrin Kadel, Lukas Scheller, Alexander M. Leipold, Tobias Krammer et autres
Abstract We report a fatal case of parkinsonism following treatment with ciltacabtagene autoleucel (cilta-cel). To investigate underlying mechanisms, we performed a multipronged longitudinal analysis using single-cell RNA (scRNA)/T-cell receptor (TCR) sequencing, flow cytometry, and cytokine measurements including cerebrospinal fluid (CSF) and peripheral …
Accès ouvert
2026
supplementary-materials
OpenAlex
Sofie-Katrin Kadel, Lukas Scheller, Alexander M. Leipold, Tobias Krammer et autres
Supplementary Figure 1 illustrates the longitudinal course of myeloma-related parameters throughout the patient’s treatment, as well as the therapeutic response assessed by ^68Ga-Pentixafor PET/CT. Supplementary Figure 2 shows the BCMA-CAR integration sites in the patient’s genome and their distribution Supplementary Figure 3 …
Accès ouvert
2026
other
OpenAlex
Sofie-Katrin Kadel, Lukas Scheller, Alexander M. Leipold, Tobias Krammer et autres
Supplementary Table 1 summarizes the lines of therapy administered prior to CAR T cell therapy. Supplementary Table 2 presents myeloma parameters and additional laboratory findings obtained immediately before the initiation of lymphodepleting chemotherapy of the index patient. Supplementary Table 3 details the …