Epithelia Realize Nematopolar Topological Defect Structures
Tianxiang Ma, Niels de Graaf Sousa, Valeriia Grudtsyna, Farzan Vafa et autres
We introduce a shape-based polar order parameter that captures the structural asymmetry of cells within epithelial monolayers. By combining bright-field imaging and traction force microscopy, we demonstrate that shape polarity serves as a unifying biomechanical metric, integrating the physical information encoded by …