Zhongting Lv

Formononetin Alleviates Cigarette Smoke Extract-Induced Lung Injury in Mice with Gut Microbiota and Taurine/SLC6A6/NF-κB Modulation

Zheng Ma, 胡森, Zhongting Lv, Shuang Liu et autres

Cigarette smoke exposure is a major preventable risk factor for respiratory disease and drives oxidative and inflammatory lung injury, highlighting the urgent need for safe, multi-target interventions beyond conventional anti-inflammatory therapy. Formononetin (FMN), a naturally occurring isoflavone with antioxidant, anti-inflammatory, and microbiota-modulating …

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Single-nucleus transcriptomics reveals cell-type-resolved brain responses to concurrent exposure to polyethylene nanoplastics and butyl benzyl phthalate

Yitong Lu, Houdao Ren, Zhongting Lv, Tiehua Zhang et autres

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Ginsenoside Rh1 Modulates GABAergic Inhibitory Homeostasis and Mitochondrial Quality Control During Lead (Pb)-Associated Neuronal Dysfunction

Xiang Li, Tingting Wang, Linfeng Mo, Huixin Cao et autres

Disruption of neuronal excitation-inhibition balance and mitochondrial quality control may contribute importantly to lead (Pb)-induced neurotoxicity, but nutritional modulators targeting these processes remain poorly characterized. This study investigated the protective effects and underlying mechanisms of ginsenoside Rh1, a ginseng-derived bioactive compound, in …

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Genistein Protects Against Lead-Induced Cognitive Impairment Through a Glutathione-Dependent Redox–Mitochondrial Apoptosis Axis

Zhongting Lv, Zeyu Ma, Yong Pang, H Y Wang et autres

Lead exposure remains a pervasive environmental and public health threat, imposing a substantial burden of neurodevelopmental and cognitive dysfunction, yet safe mechanism-oriented interventions remain limited. Genistein, a soybean-derived isoflavone with antioxidant and neuroprotective potential, may counter heavy metal-induced neural injury; however, whether …

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Toxicological impacts of neonicotinoid insecticides in zebrafish: A review of individual and mixture toxicity

Shuang Liu, J J Lu, Zhongting Lv, Jie Zhang et autres

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Bilobalide attenuates chronic restraint stress-induced neurotoxicity and cognitive impairment through glucocorticoid receptor-dependent BDNF/TrkB/PI3K/Akt signaling

Zhongting Lv, Xiang LI, Hanning Wu, Xiaowen Zhang et autres

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