A transient CD87-centred axis enhances the Th17 potential of cDC2 in neonates
Ramin Shakiba, Doğuş Altunöz, Kaushikk Ravi Rengarajan, Steven X. Cho et autres
Abstract Type 2 conventional dendritic cells (cDC2) orchestrate T cell immunity, yet the signals that regulate their tissue-specific functions across development remain poorly defined. We demonstrate that splenic cDC2/DC3 subset heterogeneity is established perinatally and that splenic ESAM hi cDC2A undergo a …
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