Prolonged high-density culture with restricted medium renewal induces epithelial-like plasticity in apical papilla stem cells
Kameliya Kercheva, Marina Miteva, Silvia Kalenderova, Vanyo Mitev et autres
Stem cells from the apical papilla (SCAPs) are dental mesenchymal stem cells known for their high proliferative and multilineage potential. However, prolonged in vitro expansion may alter their phenotype due to microenvironmental stress. This exploratory study aimed to investigate whether prolonged high-density …
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Biomolecules and Biomedicine