A proposed North American approach for genetic testing of individuals at risk for malignant hyperthermia
Sheila Riazi, Stacey Watt, Jennifer Plester, Leslie G. Biesecker
Malignant hyperthermia, a pharmacogenetic disorder of skeletal muscle, is a potentially fatal reaction triggered by exposure to volatile anesthetics or succinylcholine. Genetic testing of the three known involved genes (RYR1, CACNA1S, and STAC3) has become the first line of testing for malignant …
ca, us (code pays fourni par la source)