Pharmacodynamic profiles inform systematization, efficacy and whole-brain drug distribution profiles in 18 antidepressants
Benjamin Hänisch, Sofie L. Valk
Although empirical evidence shows that antidepressants are effective and superior to placebo in treating depressive disorders, their mechanisms of action are still unclear. In this study, we examine the multidimensional molecular affinities of 18 commonly used antidepressants. Clustering analyses consistently generate three …
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bioRxiv (Cold Spring Harbor Laboratory)