A multivalent peptide-polymer conjugate material mimics STING to therapeutically activate innate immune signaling
Justin A Kaskow, Julia Treese, Anita Gaenko, Victoria F. Gomerdinger et autres
Stimulator of interferon genes (STING) is a promising therapeutic target for cancer immunotherapy, but agonists are often rendered ineffective by the loss of STING expression in cancer cells. Here we engineer a multivalent peptide-polymer conjugate material that can easily be delivered to …
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bioRxiv (Cold Spring Harbor Laboratory)