Human ILC methylomes uncover stable lineage codes and disease-linked ILC2 regulators in allergy
Ayush Jain, Elia C. Diem, Chia-wen Lu, Matthias Steglich et autres
Abstract The transcriptional programs of human ILCs are increasingly defined, but the DNA-methylation landscapes that stabilize their identity and function remain poorly understood. Here, we generated genome-wide DNA methylomes of human NK cells, ILC1, ILC2, and ILC3 from blood and lymphoid tissues. …
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bioRxiv (Cold Spring Harbor Laboratory)