Chiral methionine oxidation reagents reveal stereospecific proteome modifications
Angel Gonzalez-Valero, Annika C. S. Page, Jayde M. Bertoch, Fadi Alsarhan et autres
Abstract Life is predicated on chirality, a molecular asymmetry akin to the left and right versions of human hands. Here we show that privileged protein residues are predisposed for chiral regulation. We developed enantiomeric oxaziridine reagents that systematically identify pro-( S ) …
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bioRxiv (Cold Spring Harbor Laboratory)