Weiping Wen

Association of multidisciplinary team management with survival in sinonasal malignancies: a real-world IPTW cohort study

Huanhuan Lyu, Hang Li, Rui He, Yaqiong Lu et autres

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Retraction: Neoadjuvant Adebrelimab Plus Chemotherapy in Untreated Locally Advanced Head and Neck Squamous Cell Carcinoma: Efficacy and Biomarker Insights From a Single-Arm Phase II Trial

Ruihua Fang, Wen Lei, Bixue Huang, Le Chen et autres

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Quantitative dynamic full-field optical coherence tomography for high-resolution intraoperative imaging of head and neck squamous cell carcinoma

Zixuan Huang, Mengyun Zhou, Zhongzhou Luo, K Chen et autres

We present a dynamic full-field optical coherence tomography (D-FFOCT) system providing both structural and dynamic contrast for label-free imaging of head and neck squamous cell carcinoma (HNSCC). The system simultaneously acquires structural and dynamic contrast, enabling visualization of tissue morphology and intracellular …

Supplementary document for Quantitative dynamic full-field optical coherence tomography for high-resolution intraoperative imaging of head and neck squamous cell carcinoma - 7942759.pdf

Zixuan Huang, Mengyun Zhou, Zhongzhou Luo, K Chen et autres

Representative examples of the Cellpose-SAM-assisted segmentation and manual-correction workflow used for quantitative analysis

Supplementary document for Quantitative dynamic full-field optical coherence tomography for high-resolution intraoperative imaging of head and neck squamous cell carcinoma - 7942759.pdf

Zixuan Huang, Mengyun Zhou, Zhongzhou Luo, K Chen et autres

Representative examples of the Cellpose-SAM-assisted segmentation and manual-correction workflow used for quantitative analysis

Supplementary document for Quantitative dynamic full-field optical coherence tomography for high-resolution intraoperative imaging of head and neck squamous cell carcinoma - 7942759.pdf

Zixuan Huang, Mengyun Zhou, Zhongzhou Luo, K Chen et autres

Representative examples of the Cellpose-SAM-assisted segmentation and manual-correction workflow used for quantitative analysis

Quantitative dynamic full-field optical coherence tomography for high-resolution intraoperative imaging of head and neck squamous cell carcinoma

Zixuan Huang, Mengyun Zhou, Zhongzhou Luo, K Chen et autres

We present a dynamic full-field optical coherence tomography (D-FFOCT) system providing both structural and dynamic contrast for label-free imaging of head and neck squamous cell carcinoma (HNSCC). The system simultaneously acquires structural and dynamic contrast, enabling visualization of tissue morphology and intracellular …

The PROFOUND study: A large-scale prospective multicenter case-control trial of a multi-cancer early detection (MCED) test in China.

K Chen, Xiang‐Yu Zhao, Guo-Yue Lv, Danbo Wang et autres

10541 Background: Early cancer detection reduces morbidity and mortality, but current recommended screening in China misses many lethal cancers. Emerging liquid biopsy-based MCED tests have the potential to increase the number of screen-detected cancers when added to recommended screening. In this study, …

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RETRACTED: Neoadjuvant adebrelimab plus chemotherapy in untreated locally advanced head and neck squamous cell carcinoma: Efficacy and biomarker insights from a single-arm phase 2 trial.

Ruihua Fang, Wen Lei, Bixue Huang, Le Chen et autres

6106 Background: Improving outcomes for locally advanced head and neck squamous cell carcinoma (LA-HNSCC) requires novel strategies. This phase 2 trial evaluated the efficacy and safety of neoadjuvant adebrelimab (a PD-L1 inhibitor) combined with chemotherapy in untreated, resectable LA-HNSCC. Methods: In this …

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Management of Parapharyngeal Benign Tumors via Combined Transcervical–Submandibular and Transoral Endoscopic Approach

Zhangwei Hu, Renqiang Ma, Jie Deng, Wei Sun et autres

BACKGROUND: To compare outcomes of the combined transcervical-submandibular and transoral endoscopic approach versus the open transcervical parotid approach and transoral endoscopic surgery alone, and to clarify the indications and advantages of the combined technique. METHODS: This retrospective observational study was conducted at …

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Neoplasm Adverse Events Associated With Anti‐Type 2 Biologics: An FAERS Database Pharmacovigilance Analysis Study

Wen Lyu, Rui Xu, Le Chen, Wen Lei et autres

BACKGROUND: Biologics targeting Type 2 immune responses, such as omalizumab (anti-IgE), dupilumab (anti-interleukin-4 receptor alpha, anti-IL-4Rα), benralizumab (anti-IL-5R), reslizumab, and mepolizumab (anti-IL-5), are increasingly used clinically. Emerging evidence suggests potential associations between biologics and neoplastic events. METHODS: We analyzed the FDA Adverse …

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Comparative validation of current staging systems in sinonasal soft tissue sarcomas: a population-based analysis

Jingtao Lin, Weiping Wen, Yihui Wen

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