Yihui Wen

Association of multidisciplinary team management with survival in sinonasal malignancies: a real-world IPTW cohort study

Huanhuan Lyu, Hang Li, Rui He, Yaqiong Lu et autres

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The PROFOUND study: A large-scale prospective multicenter case-control trial of a multi-cancer early detection (MCED) test in China.

K Chen, Xiang‐Yu Zhao, Guo-Yue Lv, Danbo Wang et autres

10541 Background: Early cancer detection reduces morbidity and mortality, but current recommended screening in China misses many lethal cancers. Emerging liquid biopsy-based MCED tests have the potential to increase the number of screen-detected cancers when added to recommended screening. In this study, …

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Response to letter regarding “artificial intelligence-assisted real-time nasopharyngeal cancer diagnostic model enhances rhinologist performance: a prospective multi-reader study”

Rui He, Yihui Wen

To the EditorWe sincerely thank Hu and Ji for their thoughtful and constructive comments on our article and appreciate the opportunity to clarify the intended scope and translational positioning of...

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Comparative validation of current staging systems in sinonasal soft tissue sarcomas: a population-based analysis

Jingtao Lin, Weiping Wen, Yihui Wen

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Development of a Microsurgical Simulator for Laryngeal Surgery: A Novel Training Device

Yihui Wen, Jie Deng, Wen Lei

ABSTRACT Objective To develop and validate a modular, low‐cost, and anatomically realistic microsurgical simulator for endolaryngeal training, including CO 2 laser procedures and microsuturing. Methods We developed a dual‐module simulator consisting of a laryngeal specimen fixation unit and a flexible laryngoscope holder. …

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Dendrobium officinale polysaccharide ameliorate hyperlipidemia through LKB1/AMPK and CD36/PGC-1α/UCP1 activation and gut microbiota modulation

Yumeng Gong, Hong Fang, Liujin Wu, Jing Zhang et autres

Dendrobium officinale polysaccharide (DOP) is recognized for its potential therapeutic effects on hyperlipidemia; however, its specific mechanisms in modulating lipid metabolism within hepatic and adipose tissues, along with its influence on the gut microbiota, have yet to be fully elucidated. Our study …

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Unhealthy sleep patterns and irregular night shift work are associated with increased risk of allergic rhinitis: a large prospective cohort study

Wen Lyu, Yihui Wen, Lie Chen, Z. Huang et autres

BACKGROUND: The influence of circadian disruption from night shift work and poor sleep on allergic rhinitis (AR) risk remains inadequately characterized. The objective of this study was to advance the understanding of how circadian disruption influence AR risk, thereby providing new insights …

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Prognostic Significance of Eosinophil Extracellular Traps in Chronic Rhinosinusitis and Innovative Nanosheets‐Based Clearance Therapy

Changhui Chen, Hang Li, Yilin Hou, Yihui Wen et autres

ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) can be classified into Eosinophilic CRSwNP (ECRSwNP) and non‐Eosinophilic CRSwNP (nECRSwNP) based on eosinophilic infiltration in nasal polyps. However, no consensus criteria exist for eosinophilic infiltration in nasal polyps, including different cutoffs for eosinophil …

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Artificial intelligence-assisted real-time nasopharyngeal cancer diagnostic model enhances rhinologist performance: a prospective multi-reader study

Rui He, Pengyu Jie, Zhangfeng Wang, Lu Yin et autres

Background Nasopharyngeal carcinoma (NPC) poses significant diagnostic challenges due to the anatomical complexity of the nasopharynx and reliance on endoscopic visual interpretation, often leading to delayed detection and unnecessary biopsies. Although artificial intelligence (AI) algorithms have shown promise in enhancing endoscopic cancer …

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Artificial intelligence-assisted real-time nasopharyngeal cancer diagnostic model enhances rhinologist performance: a prospective multi-reader study

Rui He, Pengyu Jie, Zhangfeng Wang, Yaqiong Lu et autres

Nasopharyngeal carcinoma (NPC) poses significant diagnostic challenges due to the anatomical complexity of the nasopharynx and reliance on endoscopic visual interpretation, often leading to delayed detection and unnecessary biopsies. Although artificial intelligence (AI) algorithms have shown promise in enhancing endoscopic cancer diagnosis, …

Artificial intelligence-assisted real-time nasopharyngeal cancer diagnostic model enhances rhinologist performance: a prospective multi-reader study

Rui He, Pengyu Jie, Zhangfeng Wang, Yaqiong Lu et autres

Nasopharyngeal carcinoma (NPC) poses significant diagnostic challenges due to the anatomical complexity of the nasopharynx and reliance on endoscopic visual interpretation, often leading to delayed detection and unnecessary biopsies. Although artificial intelligence (AI) algorithms have shown promise in enhancing endoscopic cancer diagnosis, …

Overall Strategy for Promoting Value Realization of Ecological Products Toward 2035

Yihui Wen, Guihuan Liu, Jinnan Wang, Yijie Liu et autres

Establishing a mechanism for the value realization of ecological products is crucial for promoting ecological development in China and for achieving the goals of carbon peaking and carbon neutrality. It also paves a new path for common prosperity for all the people …

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