Accès ouvert
2026
article
OpenAlex
Tomoaki Kameda, Shunichi Okada, Takahito Nishihira, Risa Suzuki et autres
Bath-related stroke is an important but underrecognized clinical problem during colder seasons. In Japan and other East Asian regions, where hot-water immersion bathing is common, individuals often bathe under cold ambient conditions, which may induce substantial hemodynamic fluctuations. However, the association between …
jp
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Accès ouvert
2026
article
OpenAlex
Hirotoshi Imamura, Nobuyuki Sakai, Tsuyoshi Ohta, Mikito Hayakawa et autres
BACKGROUND AND PURPOSE: Prehospital assessment is important for transporting patients with large vessel occlusion (LVO) to hospitals that are capable of intravenous thrombolysis and/or mechanical thrombectomy. Although its simplicity and accuracy are difficult to reconcile, we aimed to create an accurate prehospital …
jp
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Accès ouvert
2026
article
OpenAlex
Yoshito Arakaki, Kaori Miwa, Masatoshi Koga, Sohei Yoshimura et autres
BACKGROUND: To what extent cerebral small vessel disease (SVD) contributes to functional disability remains unclear. We investigated the longitudinal effect of SVD burden on functional decline. METHODS: In this investigator-initiated, prospective, multicenter, and observational study, patients receiving oral antithrombotic therapy for cerebrovascular …
jp
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Accès ouvert
2026
article
OpenAlex
Kaori Miwa, Masatoshi Koga, Kanta Tanaka, Yusuke Yakushiji et autres
INTRODUCTION: To investigate the association of intracranial atherosclerotic disease (ICAD), alone and comorbid with cerebral small vessel disease (SVD), with ischemic or hemorrhagic events in patients receiving antithrombotic therapy. PATIENTS AND METHODS: In this prospective, multicenter, observational study, baseline brain MRI was …
jp
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Accès ouvert
2026
article
OpenAlex
Takeshi Yoshimoto, Masafumi Ihara, PN Sylaja, Jean‐Benoît Rossel et autres
Background and Purpose: We aimed to evaluate whether early versus late initiation of direct oral anticoagulant (DOAC) after acute ischemic stroke (AIS) yields different safety and efficacy outcomes in Asian versus non-Asian patients. Methods: We analyzed Early versus Late initiation of direct …
jp, in, ch, de, at, it, be, pt, gb
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Accès ouvert
2026
conference-abstract
OpenAlex
Yuhei Anan, Tadashi Ozawa, Masayuki Suzuki, Akito Mori et autres
Abstract Background and aims This study aimed to clarify the clinical characteristics that distinguish multiple acute perforating artery infarctions from single infarctions. Methods We identified 834 patients with acute ischemic stroke confined to perforating artery territories. Patients were classified into multiple (n …
jp
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Accès ouvert
2026
conference-abstract
OpenAlex
Takeshi Yoshimoto, Masafumi Ihara, PN Sylaja, Jean‐Benoît Rossel et autres
Abstract Background and aims Asians have a higher incidence of intracerebral hemorrhage than non-Asians. We aimed to evaluate whether early versus late initiation of direct oral anticoagulation (DOAC) after acute ischemic stroke (AIS) yields different safety and efficacy outcomes in Asian versus …
jp, in, ch
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Accès ouvert
2026
conference-abstract
OpenAlex
Yuki Sakamoto, Kazunori Toyoda, Shigeru Fujimoto, Iguchi Yasuyuki et autres
Abstract Background and aims In hyperacute lacunar stroke, the symptoms are usually mild, and the mechanism is not primarily embolic; therefore, the clinical benefit of intravenous rt-PA remains uncertain. Early dual antiplatelet therapy (DAPT) may reduce early neurological deterioration with a lower …
jp
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Accès ouvert
2026
article
OpenAlex
Takeshi Yoshimoto, Masafumi Ihara, PN Sylaja, Jean-Benoît Rossel et autres
Background And Purpose We aimed to evaluate whether early versus late initiation of direct oral anticoagulant (DOAC) after acute ischemic stroke (AIS) yields different safety and efficacy outcomes in Asian versus non-Asian patients.Methods We analyzed Early versus Late initiation of direct oral …
us, at
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Accès ouvert
2026
article
OpenAlex
Ryoma Inui, Kanta Tanaka, Kazunori Toyoda, Sohei Yoshimura et autres
BACKGROUND: This study aimed to evaluate the real-world status of endovascular therapy for acute ischemic stroke >24 hours after onset. METHODS: From the data set of Japan Stroke Data Bank, a nationwide, multicenter prospective registry of stroke within 7 days of onset, …
jp
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Accès ouvert
2026
article
OpenAlex
Soya Iwamoto, Kaori Miwa, Masatoshi Koga, Sohei Yoshimura et autres
BACKGROUND AND OBJECTIVES: Enlarged perivascular spaces (ePVSs) are considered to increase the risk of stroke. However, data regarding the benefits and risks of antithrombotic therapy in patients with ePVSs are currently limited. This study assessed the association between ePVSs and the risks …
jp
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Accès ouvert
2026
article
OpenAlex
Shigeru Fujimoto, Yasuyuki Iguchi, Hiroshi Yamagami, Masatoshi Koga et autres
AIM: To explore whether the antiplatelet effects of prasugrel and clopidogrel vary according to patient background factors in the ACUTE-PRAS study. METHODS: This was a post hoc, hypothesis-generating, exploratory analysis of the multicenter, open-label, randomized controlled ACUTE-PRAS study, in which 176 patients …
jp, in, de, gb, us
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