Proteinuria in Porcine Kidney Xenografts: Beyond Immunologic Failure
Kinoshita et al1 demonstrate prolonged porcine kidney xenograft survival under TNX-1500, but persistent nephrotic-range proteinuria remains a major limitation to long-term graft durability. The underlying mechanisms driving this functional incompatibility remain insufficiently defined, particularly as xenografts enter early clinical translation. We outline …
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Transplantation