Accès ouvert
2026
article
OpenAlex
Yongfu Wang, Wei Liu, Pengzhuo Tao, Changmin Liu et autres
BACKGROUND: Lung adenocarcinoma (LUAD) is a leading cause of cancer death. Neurotensin receptor 1 (NTSR1), a G protein-coupled receptor, is overexpressed in LUAD and linked to poor prognosis, but its therapeutic potential is underexplored. METHODS: This study combined multi-database bioinformatics to systematically …
cn
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Accès ouvert
2026
article
OpenAlex
Changmin Liu, Yongfu Wang, Wei Liu, Yizhen Yuan et autres
Background: One of the main causes of cancer-related mortality globally is lung adenocarcinoma (LUAD), necessitating the development of novel therapeutic targets. The parathyroid hormone type 2 receptor (PTH2R) exhibits differential expression across multiple cancers, yet its role in LUAD remains unclear. Methods: …
cn, my
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Pengzhuo Tao, Wei Liu, Yongfu Wang, Yajing Xue et autres
Background: Advanced lung adenocarcinoma (LUAD) is the leading cause of cancer-related deaths, with existing treatments hampered by drug resistance. This underscores the urgent need to identify novel therapeutic targets. The role of neuropeptide Y (NPY) receptors in LUAD remains unclear, and this …
cn, my
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Yajing Xue, Wei Liu, Yongfu Wang, Pengzhuo Tao et autres
The incidence and mortality rates of lung adenocarcinoma (LUAD) continue to rise, highlighting an urgent need for novel therapeutic targets. In this study, bioinformatics analysis revealed that members of the metabotropic glutamate receptor (mGluR) family are significantly correlated with the expression profile, …
cn
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Accès ouvert
2026
article
OpenAlex
Yizhen Yuan, Yongfu Wang, Wei Liu, Changmin Liu et autres
Lung adenocarcinoma (LUAD) remains the leading cause of cancer-related mortality worldwide, highlighting the urgent need for novel therapeutic targets. While the role of the somatostatin receptor (SSTR) family is well established in neuroendocrine tumors, their expression patterns, clinical significance, and therapeutic potential …
cn
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