2026
article
OpenAlex
Jessy Alexander, Harbir Singh
Abstract Introduction The complement system performs diverse functions spanning immune surveillance, pathogen defense, and developmental regulation. Upon antigen recognition, antigen—antibody immune complexes (ICs) activate complement and are opsonized with C3b. In humans, C3b-opsonized ICs bind to complement receptor 1 (CR1) on erythrocytes …
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2026
article
OpenAlex
Alexander Jacob, Harbir Singh, Poolakkad S. Satheeshkumar, Aum Champaneri et autres
The complement system is a central component of innate immunity with established roles in host defense and emerging functions in neurodevelopment, synaptic remodeling, and neuroimmune communication within the central nervous system (CNS). In parallel, advances in nanotechnology have not only enabled targeted …
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Accès ouvert
2026
preprint
OpenAlex
Alexander Jacob, Harbir Singh, Satheesh Kumar Poolakkad Sankaran, Rahul Kumar Das et autres
The complement system is a central component of innate immunity with established roles in host defense and emerging functions in neurodevelopment, synaptic remodeling, and neuroimmune communication within the central nervous system (CNS). In parallel, advances in nanotechnology have enabled targeted strategies for …
us
(code pays fourni par la source)