Paolo Nucci

Late onset LHON: report of two cases with successful recovery of vision

Leonardo Bottazzi, Giorgio Lari, Nicolò Ribarich, Luigi Brotto et autres

Leber hereditary optic neuropathy (LHON) is a mitochondrial genetic disorder typically characterized by subacute vision loss in young males, whereas late-onset cases (> 40 years) are less common and are often triggered by toxic or nutritional factors. This case series reports two …

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Consensus on evidence gaps and unmet needs in childhood myopia: findings from a European Delphi study with eye care professionals and payers

W. A. Lagrèze, Paolo Nucci, Matthijs Versteegh, Caroline Klaver et autres

BACKGROUND/AIMS: Childhood myopia is a growing global concern, associated with significant burdens. This study aimed to identify evidence gaps and unmet needs in childhood myopia management through a European Delphi panel involving eye care professionals (ECPs) with expertise in childhood myopia management …

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Combined Hamartoma of the Retina and Retinal Pigment Epithelium: The Contribution of Optical Coherence Tomography in Redefining Its Development and Natural History – A Case Series

Andrea Lembo, Francesco Pichi, A. Cernuschi, Luca Marelli et autres

Introduction: Combined hamartoma of the retina and retinal pigment epithelium (CHRRPE) is a rare, benign retinal tumor typically diagnosed in childhood and traditionally believed to involve the full thickness of the retina and the retinal pigment epithelium (RPE) from early stages. With …

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Eye care adherence in pediatric and elderly: Understanding and addressing the challenges

Edoardo Villani, Alessandra Curci, Francesco Bonsignore, Diana V. Do et autres

Adherence in pediatric and elderly eye care is a system outcome shaped by patient, caregiver, treatment, service design, and affordability. This narrative review synthesizes recent evidence on magnitude, determinants, and consequences of nonadherence across a representative selection of major pediatric and older …

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Long-term outcomes after phacoemulsification and trabeculectomy in uncontrolled glaucoma and cataract in staged versus combined approaches: a single-center observational study

Matteo Sacchi, Gianluca Monsellato, Davide Rastelli, Shadan Ranaei et autres

OBJECTIVE: To assess the long-term (4 year) outcomes of staged (phacoemulsification ≥6 months prior to trabeculectomy) or combined (phacotrabeculectomy) surgical approaches in patients with uncontrolled glaucoma. METHODS AND ANALYSIS: Patients who underwent trabeculectomy alone (with phacoemulsification at least 6 months before trabeculectomy …

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Changing paediatric uveitis patterns in Italy: an eight-year experience from the Reggio Emilia Uveitis clinic

Pietro Gentile, Raffaella Aldigeri, Francesca Ceccarelli, Emanuele Ragusa et autres

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Differential Changes in Retinal Cyst Characteristics in inner versus outer retina in Diabetic Macular Edema Treated With Ang-2/VEGF-A Dual Inhibitor

Camilla Alovisi, Vanda Bucceri, Gabriele Piccoli, Celeste Limoli et autres

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Storie di ordinaria isteria: quando una bambina dice che non vede

Paolo Nucci

The case of Giulia, a nine-year-old girl with progressive visual difficulties in the absence of organic findings, illustrates a common functional presentation in paediatrics. The symptom, fluctuating and inconsistent with ocular pathology, serves a communicative and regulatory function in response to excessive …

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Rethinking the definition of “combined retinal hamartoma”: A call for taxonomical clarity

Paolo Nucci, A. Cernuschi, Stela Vujosevic

Combined hamartoma of the retina and retinal pigment epithelium (CHRRPE) has long been regarded as a congenital, full-thickness malformation involving all retinal layers and the RPE. However, advances in multimodal imaging have revealed a subset of non-pigmented, inner-retinal lesions with features distinct …

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