Ricardo da Silva Antunes

Conserved Human CD4 T Cell Targets Inform Group A Streptococcus Vaccine Design 2309249

Jessica Nevarez‐Mejia, Adam Abawi, Amin Shaik, Grazia Vento et autres

Abstract Introduction Group A Streptococcus (GAS) is a globally prevalent bacterial pathogen responsible for over 500,000 deaths annually and a leading cause of post-infectious autoimmune diseases, yet no vaccine is available. Current vaccine development focuses primarily on antibody responses to a limited …

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Whooping cough disease induces durable protection from asymptomatic re-infection 2310171

Emil Johansson, Jessica Nevarez‐Mejia, A-Reum Kim, Grazia Vento et autres

Abstract Introduction Bordetella pertussis (BP) is the causative agent of whooping cough (WC), also known as pertussis, a highly contagious respiratory disease. Although BP vaccination remains the most effective preventive measure, the shift from whole-cell pertussis (wP) vaccine to acellular pertussis (aP) …

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Comprehensive mapping of human CD4+ T cell epitopes for Nipah and measles as prototype Paramyxoviruses

Alison Tarke, Mariah Macias, Claudia Francisco Morales, Tanner Michaelis et autres

Paramyxoviruses comprise a diverse family of viruses that threaten global human health through direct infection and zoonotic transmission. Understanding adaptive immune responses to these viruses is critical for characterizing host-pathogen interactions and evaluating vaccine performance. Here, we systematically map human CD4 + …

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Author response for "Characterization of the SARS-CoV-2-specific T cell responses in Rheumatoid Arthritis subjects vaccinated for COVID-19 protection"

Jaeyoon Song, Ricardo da Silva Antunes, Mehrnaz Agili Seyede, Monica Guma et autres