Accès ouvert
2026
article
OpenAlex
Vincenzo Criscuolo, Valerio Nicolella, Carmela Polito, Rosa Sirica et autres
Abstract Background Neurofilament light chain (NfL) reflects neuro-axonal injury in multiple sclerosis (MS), but method-dependent bias limits interchangeability across automated platforms. We assessed agreement between Roche Elecsys ® and Fujirebio Lumipulse ® , evaluated Simoa-referenced harmonization, validated Elecsys ® clinical associations, and …
it
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Valerio Nicolella, Carmela Polito, Vincenzo Criscuolo, Rosa Sirica et autres
BACKGROUND: Plasma neurofilament light chain (pNfL) is an established biomarker of neuroaxonal injury in multiple sclerosis (MS), but analytical variability across platforms may limit clinical comparability. OBJECTIVE: We compared pNfL values obtained using Lumipulse® and Atellica® assays, and evaluated the clinical correlates …
it
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Evelina La Civita, Mariano Fiorenza, Giuseppe Jannuzzi, Rosa Sirica et autres
OBJECTIVES: Serum thyroglobulin (Tg) is a key biomarker in the post-surgical monitoring of differentiated thyroid cancer (DTC). However, inter-assay variability among different immunoassay platforms can impact clinical interpretation, particularly at low Tg concentrations. This study aimed to compare the analytical performance and …
it
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Evelina La Civita, Mariano Fiorenza, Giuseppe Jannuzzi, Rosa Sirica et autres
ABSTRACT Prostate‐specific antigen (PSA) is a critical biomarker for prostate cancer (PCa) patient clinical management. In this study, we sought to compare three different immunoassays (CLIA): Beckman Coulter Access Hybritech (PSA‐B) (reference method), Immulite 2000 PSA (PSA‐I) and the newly introduced Atellica …
it
(code pays fourni par la source)