Mahboubeh Pordeli

Master’s thesis

Mahboubeh Pordeli

Adenosine plays a central role in maintaining healthy communication between brain cells, yet its balance can easily shift during stress, disease, or chronic receptor stimulation. Previous studies have shown that adenosine elevation during and after cerebral ischemia alters the expression and distribution …

Contributors

Amos Olusegun Abioye, Adeboye Adejare, Adegoke O. Adeniji, Olasunmbo O. Afolayan et autres

Cholesterol, lipid metabolism, and lipid rafts in Alzheimer's disease

Changiz Taghibiglou, Mahboubeh Pordeli, Elina Setork, Francisco S. Cayabyab

ca (code pays fourni par la source)

Non-Competitive AMPA Receptor Antagonist Perampanel Inhibits Ischemia-Induced Neurodegeneration and Behavioral Deficits in Focal Cortical Pial Vessel Disruption Stroke Model

Michael G. Zaki, Mohamed Taha Moutaoufik, Mahboubeh Pordeli, Mohan Babu et autres

Glutamate receptors represent a potential target for neuroprotection in neurodegenerative neurological conditions. Perampanel, a non-competitive α-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor (AMPAR) antagonist, is clinically approved for the management of epilepsy. Perampanel's neuroprotective effects have been reported in global and focal cerebral ischemia models, but …

ca (code pays fourni par la source)

Non-Competitive AMPA Receptor Antagonist Perampanel Inhibits Ischemia-Induced Neurodegeneration and Behavioral Deficits in Focal Cortical Pial Vessel Disruption Stroke Model

Michael G. Zaki, Mohamed Taha Moutaoufik, Mahboubeh Pordeli, Mohan Babu et autres

Glutamate receptors represent a potential target for neuroprotection in neurodegener-ative neurological conditions. Perampanel, a non-competitive α-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor (AMPAR) antagonist, is clinically approved for the management of epilepsy. Perampanel’s neuroprotective ef-fects have been reported in global and focal cerebral ischemia models, but …

ca (code pays fourni par la source)

The Anti-Parkinsonian A2A Receptor Antagonist Istradefylline (KW-6002) Attenuates Behavioral Abnormalities, Neuroinflammation, and Neurodegeneration in Cerebral Ischemia: An Adenosinergic Signaling Link Between Stroke and Parkinson’s Disease

Michael G. Zaki, Elisabet Jakova, Mahboubeh Pordeli, Elina Setork et autres

Stroke, the third leading cause of death worldwide, is a major cause of functional disability. Cerebral ischemia causes a rapid elevation of adenosine, the main neuromodulator in the brain. The inhibition of adenosine A2A receptors (A2ARs) has been introduced as a potential …

ca (code pays fourni par la source)

The Anti-Parkinsonian A2A Receptor Antagonist Istradefylline (KW-6002) Attenuates Behavioral Abnormalities, Neuroinflammation, and Neurodegeneration in Cerebral Ischemia: Adenosinergic Signaling Link Between Stroke and Parkinson’s Disease

Michael G. Zaki, Elisabet Jakova, Mahboubeh Pordeli, Elina Setork et autres

Stroke, the third leading cause of death worldwide, is a major cause of functional disability. Cerebral ischemia causes rapid elevation of adenosine, the main neuromodulator in the brain. Inhibition of adenosine A2A receptors (A2ARs) has been introduced as a potential target in …

ca (code pays fourni par la source)