Mario Keko

Effect of CT-based material grouping on finite element strength and stiffness predictions in vertebrae with metastatic lesions

Daniel Strack, Nil Rehtanz, Zahra Soltani, Mario Keko et autres

Abstract Introduction Metastatic spinal lesions substantially alter vertebral mechanical properties and increase fracture risk. Computed tomography (CT)-based finite element (FE) models can estimate vertebral strength, but their accuracy depends on how CT-derived material properties are represented. This study evaluated the effect of …

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Fat grafting in soleal sling syndrome: a retrospective case series

Laura Hilbig‐Vlatten, Miguel I. Dorante, Julius Asschenfeldt, Lilly F. Stadelmeier et autres

Soleal sling syndrome (SSS) is an underrecognized cause of tibial nerve (TN) entrapment at the popliteal fossa, resulting in exertional calf pain, paresthesia and functional impairment. Five patients (seven limbs) underwent decompression with autologous fat grafting. Clinical improvement occurred without graft-related complications, …

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Deep Learning-Based Classification of Bone Lesions on CT Scans of Metastatic Spine Disease Patients: A 3D-Convolutional Neural Network Approach

Bülent Aslan, Nazim Haouchine, Steve Pieper, Steve Pieper et autres

ABSTRACT Purpose Clinical assessment of vertebral lesion quality (osteolytic, osteoblastic, mixed) remains subjective, with limited interobserver reliability. This study evaluated a novel application of 3D convolutional neural networks (3D-CNNs) for classifying lesion quality from CT volumes in metastatic cancer patients. Materials and …

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Socioeconomic and Demographic Influences on Trigger Finger Management: A Retrospective Cohort study

Lilly F. Stadelmeier, Laura Hilbig‐Vlatten, Julius Asschenfeldt, Christine O. Kang et autres

Background: Surgical disparities often stem from social determinants beyond underlying pathology. This study aims to examine how race, socioeconomic factors, and insurance status affect the management of trigger finger, one of the most common hand conditions treated in the United States. Methods: …

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Impact of prior conventional irinotecan use on nanoliposomal irinotecan efficacy in advanced pancreatic cancer: a meta-analysis

Seohyuk Lee, T.L. Correa, V. Birda, Keyan Roshan et autres

BACKGROUND: Nanoliposomal irinotecan (nal-IRI) has become an established therapy for advanced pancreatic ductal adenocarcinoma (PDAC), both in the post-gemcitabine setting and, more recently, in the first-line NALIRIFOX regimen. Concerns remain regarding cross-resistance in patients previously exposed to conventional irinotecan. We performed a …

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Wearable Electrical Impedance Myography for Continuous, Non-Invasive Detection of Acute Compartment Syndrome: A Preclinical Feasibility Study

Mohammad Javad Shariyate, Mohammad Khak, Buket Sonbas-Cobb, Maria V. Velasquez Hammerle et autres

INTRODUCTION: Acute compartment syndrome (ACS) is a limb-threatening complication of extremity trauma that requires timely diagnosis to prevent irreversible muscle and nerve injury. Current diagnostic methods are invasive, intermittent, and operator-dependent. We evaluated the feasibility of a novel, Bluetooth-enabled electrical impedance myography …

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The Persistent Preference for Traditional Bonesetting in Ethiopia: Risk Factors and Missed Opportunities

Mengistu G Mengesha, Morgan Askew, Abdoulie Njai, Ephrem G Adem et autres

Introduction: Many patients in Ethiopia prefer traditional bonesetting (TBS) over formal health services for musculoskeletal injuries, despite well-documented complications. We analyzed risk factors for initial and persistent TBS preference among patients who patronized TBS and subsequently presented to a tertiary hospital for …

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Effect of Cannabis Use on Revision Surgery After Lumbar Spine Fusion

H. von Riegen, Erica Greiner, Christopher Lai, Michael Akodu et autres

Objective: Lumbar arthrodesis is commonly required for a number of spinal pathologies. The increasing use of cannabis and its legalization in many countries has the potential to impact spine surgical outcomes. There is a scarcity of research on the association between cannabis …

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Multimodal characterization of articular cartilage degeneration in the humeral head using Raman spectroscopy, biomechanics, and imaging

Mason Garcia, Dev R. Mehrotra, Jake Giering, Erik E. Ersland et autres

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Association of Charlson Comorbidity Index and Charlson Fracture Index With Surgical Complications in Distal Radius Fractures: A Retrospective Review

Amber M. Parker, Nicholas Genovese, Alexy Ilchuk, Carl M. Harper et autres

Purpose: To assess and compare the associative value of comorbidity fracture-specific index (CFI) versus the Charlson comorbidity index (CCI) in identifying patients at risk for early complications after open reduction and internal fixation (ORIF) of distal radius fractures (DRFs). Methods: We performed …

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Radiation Dose and Lymphedema Risk After Immediate Lymphatic Reconstruction and Axillary Lymph Node Dissection

Daphna Y. Spiegel, Josephine Levey, Mario Keko, Anna M. Modest et autres

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Metastatic Spine Disease Alters Vertebral Load‐To‐Strength Ratios in Cancer Patients Compared to Healthy Individuals

D C Anderson, Mario Keko, Joanna N. James, Brett T. Allaire et autres

Purpose: This study investigated the effect of bone metastasis on the biomechanical environment of human vertebrae in patients with metastatic spine disease through the metric of load-to-strength ratio (LSR). Specifically, we compared the patients' LSRs to age and sex-similar noncancer controls from …

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