Ningning Wang

PGT-M Offers a Strategy for Epileptic Women with Monogenic Disorders Caused by FLNA Mutation

Yu Luo, Yicong Liu, Yan Xu, Heyu Zhang et autres

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PD ‐ L1 Tumour‐Cell/Immune‐Cell Phenotype, Early Nodal Status and Serum Biomarkers in Locally Advanced Head and Neck Squamous Cell Carcinoma Receiving Neoadjuvant Therapy: A Retrospective Cohort Study With Exploratory Survival Analysis

Ningning Wang, Zehui Yun, Fangli Cao

PD-L1 tumour-cell (TC) and immune-cell (IC) expression are scored separately in head and neck squamous cell carcinoma (HNSCC) but are often collapsed into a combined positive score, potentially obscuring distinct patterns. In this retrospective, single-centre cohort of 61 patients with locally advanced, …

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Nuclear factor I-C as a novel candidate regulator in postoperative atrial fibrillation: integrated omics and proof-of-concept validation

Chaoyue Gao, Yue Shu, Lin Luo, Ningning Wang et autres

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The Prognostic Implications of Discordance Between PD-L1 Expression and Early Lymph Node Metastasis in Hypopharyngeal Squamous Cell Carcinoma

Ningning Wang, Zehui Yun, Fangli Cao

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Arsenic-induced hepatotoxicity: Mechanistic insights into TNFAIP3-mediated regulation of the NF-κB p65/IAPs Signaling Pathway

Baiming Jin, Haonan Li, Hua Zhang, Lele Liu et autres

Exposure to excessive arsenic results in progressive liver injury, although the underlying mechanisms are not yet fully elucidated. This study aims to investigate whether TNFAIP3 plays a protective role within the transcriptional regulatory network linking with NF-κB p65 and IAPs. A model …

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Passivation effects of different ratios of fly ash and straw on heavy metals in coal gangue-contaminated soil in Guizhou Province, China

Xiuyue Xu, Jun Ren, Ningning Wang, Hui Dong

To simultaneously achieve the stabilization of heavy metals in coal gangue- contaminated soil and the resource utilization of solid waste, fly ash (FA) and corn straw (CS) were adopted as passivators to construct a low-cost and sustainable remediation system. Through pot experiments, …

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Influence of distillery sewage sludge application placement methods on microbial community functions in sorghum rhizosphere: Focus on nitrogen and phosphorus cycling

Hongpei Lu, Yonggui Wu, Youfa Luo, Jiayi Yuan et autres

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Asian consensus statement of experts on thermal ablation for secondary hyperparathyroidism in chronic kidney disease

Huihui Chai, Wenwen Yue, Liping Sun, Ling Zhang et autres

Secondary hyperparathyroidism (SHPT) is characterized by parathyroid hyperplasia, persistently elevated parathyroid hormone levels, and disturbances in mineral metabolism. Currently, a considerable amount of literature has consistently shown that thermal ablation is effective in maintaining parathyroid hormone levels within an appropriate range, normalizing …

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A MERS-CoV-like mink coronavirus uses ACE2 as an entry receptor

Ningning Wang, Weiwei Ji, Houqi Jiao, Michael Veit et autres

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Prediction of intradialytic hypotension based on heart rate variability and skin sympathetic nerve activity using LASSO-enabled feature selection: a two-center study

Yike Zhang, Shuang Su, Zhenye Chen, Yaoyu Huang et autres

Background Intradialytic hypotension (IDH) is a prevalent complication during hemodialysis (HD). However, conventional predictive models are imperfect due to multifaceted etiologies underlying IDH.Methods This study enrolled 201 patients undergoing maintenance HD across two centers. Seventy percent of the patient cohort was randomly …

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T cell receptor activation contributes to brain damage after intracerebral hemorrhage in mice

Yuwen Xiu, Yingjie Wang, Ningning Wang, Ning Liu et autres

BACKGROUND: Our previous studies demonstrated that activated T cells accumulate in perihematomal regions following intracerebral hemorrhage (ICH) and exacerbate hemorrhagic brain injury. In the present study, we aimed to explore the mechanisms underlying brain-infiltrating T cell activation and the associated pathophysiological effects …

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Gut microbiota and OMVs: Unveiling novel regulatory mechanisms in high‐altitude myocardial injury

Mingyang Chang, Yongqiang Zhou, Tiantian Xia, Pan Shen et autres

The gut microbiota influences host health, with outer membrane vesicles (OMVs) facilitating intercellular communication and transporting bioactive molecules. At high altitudes, OMVs can cross the intestinal barrier, affecting heart function and potentially modulating inflammation, oxidative stress, and apoptosis in cardiomyocytes. Genetic engineering …

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