Yingjie Wang

LncRNA ACTA2-AS1 acts as a bladder cancer prognostic biomarker and blocks malignant advance via miR-148b-3p/DNAJB4

X P Chen, Qunfu Tang, Yingjie Wang, Jianbin Zhang et autres

BACKGROUND: Long non-coding RNA (lncRNA) is crucial in bladder cancer (BCa) development. This research explores the clinical significance and underlying mechanisms of lncRNA ACTA2-AS1 in BCa. METHODS: From the GEO database, differentially expressed lncRNAs (DElncRNAs) in BCa were identified, and tumor, along …

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LncRNA HMGA2-AS1 promotes postoperative recurrence in non-muscle-invasive bladder cancer by sponging miR-367-3p to activate YAP1

Yingjie Wang, Zhen Nai, Jianbin Zhang

BACKGROUND: Non-muscle-invasive bladder cancer (NMIBC) is characterized by a high postoperative recurrence rate. LncRNAs have emerged as key regulators in cancer progression. The clinical relevance and mechanistic role of HMGA2-AS1 in NMIBC recurrence remain unclear. METHODS: Clinical samples contained paired adjacent and …

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Insights into the critical processes of methane biogeochemical cycling in inland freshwater ecosystems: a systematic review

Shengman Zhang, Yingjie Wang, Yue Xia, Fushun Wang et autres

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Multi-Modal Encrypted Retrieval Method With Semantic Feature Fusion Towards Internet of Medical Things

Puning Zhang, Jing Wang, Yingjie Wang, Zhen Zhang

There exists a tremendous amount of multimodal data in the Internet of Medical Things (IoMT), including medical texts and corresponding images. Retrieval technology can extract target data on demand from the extensive multimodal medical data space, which is crucial for aiding diagnosis …

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Exposure of yellow mealworm (Tenebrio molitor) to graphene nanosheets and multi-walled carbon nanotubes alters metabolite and gene expression profiles

Yingjie Wang, Lu Gan, Qing Liu, Yi Cao

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Alterations in Trace Element and Metabolite Profiles by Graphene Nanosheets and Multi‐Walled Carbon Nanotubes as Soil Contaminants in Foot Tissues of the Chinese White Jade Snails ( Achatina fulica )

Yingjie Wang, Qing Liu, Zhengzheng Zhou, Liang Li et autres

The increasing applications of carbon nanomaterials (NMs) raise concerns about their potential as soil contaminants, yet predictive models for NM-related soil contamination risks remain scarce. This study established the Chinese white jade snails (Achatina fulica) as a novel model to assess the …

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Machine learning-driven clinical decision support for radical local consolidative therapy in synchronous oligometastatic NSCLC: A SEER population-based analysis of 17 cancer registries (2018–2021)

Xiaolong Hu, Dan Hu, Chen Liu, Gang Ren et autres

BACKGROUND: Synchronous oligometastatic nonsmall cell lung cancer (NSCLC) is a unique clinical entity with potential benefit from radical local consolidative therapy (LCT). However, robust tools to stratify patients most likely to benefit from radical LCT are lacking. MATERIALS AND METHODS: We identified …

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Analysis of efficacy and safety of intensity-modulated radiotherapy with “Target-Ring” strategy for stage IVA large-volume thymoma and thymic carcinoma: a single-center study

Dongshu Chang, Zhiguang Fu, Jing Li, Yupeng Di et autres

Background: Thymic tumors at stage IVA are characterized by local invasion into adjacent structures (e.g., pericardium, great vessels) and/or regional lymph node metastasis, with unresectable large-volume tumors posing unique therapeutic challenges due to their proximity to critical thoracic organs and potential for …

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Association between family doctor contract services and management status among patients with hypertension or diabetes in a multi-ethnic Province of China

Ao Zhang, Yingjie Wang, S.Y. Zhang, Yuguo Ye et autres

BACKGROUND: The family doctor contract service has emerged as a crucial model for managing chronic diseases. This study aims to examine the association between family doctor service contract and follow-up management and control among patients with hypertension and diabetes in a remote …

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Precision Cuproptosis Activation via HER2‐Targeted Bimetallic MOF Nanoreactors Breaks Metabolic Adaptation in Aggressive Breast Cancers

Mingjiang Liu, Harry H. Miao, Tong Ye, Lian See Tan et autres

Abstract Tumor heterogeneity and the single‐pathway inhibition mechanisms of trastuzumab represent major contributors to treatment failure in human epidermal growth factor receptor 2‐positive (HER2+) breast cancer. Cuproptosis, a promising copper‐dependent cell death mechanism, remains clinically constrained by its inherent reliance on copper …

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The Relationship Between Cancer Cognition, Coping Ability and Behavioral Intention of Secondary Cancer Prevention Among Rural Residents in Shandong Province

Wenning Sun, Xingli Ma, Ao Zhang, Yingjie Wang et autres

Background: Secondary prevention plays a crucial role in reducing cancer-related deaths. Previous studies have indicated that cancer cognition and coping ability significantly influence behavioral intention towards secondary prevention. However, limited research has explored the relationship between the three, particularly among rural residents. …

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Association between the e-healthy literacy and cancer prevention consciousness in rural China: cancer cognition acting as a mediator

Huifang Zhang, Xindan Zhang, Xingli Ma, Boyang Fan et autres

BACKGROUND: Cancer prevention is a critical public health challenge in China, especially among rural residents. This study aimed to examine the mediating role of cancer cognition in the relationship between e-health literacy and cancer prevention consciousness. METHODS: A multi-stage stratified random sampling …

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