2026
article
OpenAlex
Susanne Marschner, Deborah Lee, Neeta Rugg, B Brown et autres
Abstract Background Twenty‐four‐hour post‐transfusion recovery (PTR24) is a key measure of red blood cell (RBC) quality. Traditionally assessed using radioactive chromium‐51 ( 51 Cr), supply and facility limitations have prompted the need for alternatives. Biotinylation of RBCs (BioRBCs) offers a non‐radioactive method …
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2025
article
OpenAlex
Kathleen K. Kelly, Crystal Stanley, Jeff Finlon, David Buesing et autres
BACKGROUND AND OBJECTIVES: The US Food and Drug Administration guidance for cold-stored platelets (CSPs) permits storage of apheresis platelets at 1-6°C for ≤14 days. During a pilot programme, CSPs were evaluated in a large US blood centre over a 10-month period (September …
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2024
article
OpenAlex
Kathleen K. Kelly, Jeff Finlon, Stefan Fulciniti, Deborah Lee et autres
BACKGROUND: Platelets collected by the Trima Accel apheresis device (Terumo BCT) are automatically leukoreduced through a leukoreduction system (LRS) where WBCs are trapped in a conical-shaped LRS chamber. The content has been used as a valuable source of mononuclear cells for research …
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