Alexandre Perdigão

Salience Network Dynamics Across Spontaneous Attacks, Interictal Rest and Interictal Pain Imagery in Menstrually Related Migraine

Inês Esteves, Alexandre Perdigão, Ana R. Fouto, Amparo Ruiz‐Tagle et autres

The persistent sensitivity to sensory and painful stimuli of people with migraine has been associated with disruption of the salience network (SN). Although migraine is characterized by severe head pain attacks, brain changes have been observed in people with migraine in between …

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Distinct salience network dynamics between the imagery and the experience of migraine attacks

Inês Esteves, Alexandre Perdigão, Ana R. Fouto, Amparo Ruiz‐Tagle et autres

Motivation: Spontaneous migraine attacks are challenging to study and most research is performed during the interictal phase. Goal(s): A pain imagery task may be able to elicit the migraine experience, even during the symptom-free phase, particularly impacting the salience network, which is …

Disrupted salience network dynamics during the imagery of migraine attacks

Inês Esteves, Alexandre Perdigão, Ana R. Fouto, Amparo Ruiz‐Tagle et autres

Abstract Moderate to severe head pain is a hallmark of recurring migraine attacks. However, it is challenging to study patients during spontaneous attacks and most research on the brain mechanisms of pain in migraine patients has been limited to the processing of …

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Disrupted activation of pain networks during attack imagery in patients with episodic migraine

Alexandre Perdigão, Inês Esteves, Ana R. Fouto, Amparo Ruiz‐Tagle et autres

Abstract Migraine is a prevalent and disabling brain disorder characterized by recurrent headache attacks alternating with pain-free periods. Patients with migraine exhibit altered brain activation in response to experimental nociceptive stimuli compared to healthy controls, suggesting impaired pain inhibition mechanisms. However, the …

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