Salience Network Dynamics Across Spontaneous Attacks, Interictal Rest and Interictal Pain Imagery in Menstrually Related Migraine
Rattachement africain : pt, es. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
The persistent sensitivity to sensory and painful stimuli of people with migraine has been associated with disruption of the salience network (SN). Although migraine is characterized by severe head pain attacks, brain changes have been observed in people with migraine in between attacks (i.e., during the interictal phase). We hypothesized that SN dynamics may be altered in people with migraine during spontaneous attacks as well as an attack imagery task engaging sensory, emotional, and cognitive aspects of pain. To test this, we analysed the SN dynamics in patients with episodic menstrually related migraine without aura across three conditions: at rest during a spontaneous attack; during the interictal phase while performing an imagery task recalling a previous attack and at interictal rest. Healthy controls were studied in matching conditions, including rest and a non-migraine head-pain imagery. We collected functional magnetic resonance imaging (fMRI) data, using a dynamic functional connectivity (dFC) analysis to examine SN temporal features from a total of 26 participants. A significant between-group difference was observed during the pain imagery task, with people with migraine exhibiting a shorter SN dwell time than controls. Such differences were not detected during spontaneous attacks or interictal rest. The between-group difference in SN dynamics observed during the pain imagery condition suggests that this paradigm may be useful for engaging the cognitive and emotional dimensions of pain. However, further work is needed to determine whether this difference is migraine-specific or rather reflects differences in the salience and affective content of the recalled experiences.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Salience Network Dynamics Across Spontaneous Attacks, Interictal Rest and Interictal Pain Imagery in Menstrually Related Migraine
- Date Crossref
- 04/09/2026
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Instituto Politécnico de Lisboa pays non établi dans la noticeUniversité ou école supérieure
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Institute for Biotechnology and Bioengineering pays non établi dans la noticeStructure de recherche
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Algarve Biomedical Center pays non établi dans la noticeStructure de recherche
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Universidade Europeia Faculdade de Ciências da Saúde pays non établi dans la noticeUniversité ou école supérieure
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University of Lisbon pays non établi dans la noticeUniversité ou école supérieure
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Universidade Católica Portuguesa Center for Interdisciplinary Research in Health pays non établi dans la noticeUniversité ou école supérieure
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Hospital da Luz Neurology Department pays non établi dans la noticeÉtablissement de santé
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Ikerbasque pays non établi dans la noticeInstitution
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Basque Center on Cognition pays non établi dans la noticeStructure de recherche
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Instituto Superior Técnico - Universidade de Lisboa Institute for Systems and Robotics - Lisboa and Department of Bioengineering pays non établi dans la noticeUniversité ou école supérieure
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Faculdade de Medicina da Universidade de Lisboa (FMUL) Centro de Estudos Egas Moniz e Instituto de Medicina Molecular João Lobo Antunes pays non établi dans la noticeUniversité ou école supérieure
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Basque Foundation for Science Ikerbasque pays non établi dans la noticeOrganisation à but non lucratif
Instituto Politécnico de Lisboa, Institute for Biotechnology and Bioengineering et Algarve Biomedical Center, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.