Accès ouvert
2025
article
OpenAlex
Narueporn Pagowong, Kanokphong Suparan, Chanon Kunasol, Chotrawee Piriyakunthorn et autres
BACKGROUND: Previous studies have shown that gut dysbiosis correlates with cognitive impairments in both animal models and clinical settings. Additionally, alterations in gut microbiota have been linked to acute coronary syndrome (ACS). However, the relationship between gut microbiota changes and cognitive outcomes …
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Accès ouvert
2024
article
OpenAlex
Hiranya Pintana, Nattayaporn Apaijai, Adivitch Sripusanapan, Chotrawee Piriyakunthorn et autres
BACKGROUND: Doxorubicin (Dox), a chemotherapeutic agent, is known to cause chemobrain leading to cognitive decline and brain mitochondrial dysfunction. Ivabradine (Iva), hyperpolarization-activated cyclic nucleotide-gated channel blocker used for angina and arrhythmia, has been shown to be an anticonvulsant, antioxidant, and neuroprotective agent. …
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Accès ouvert
2024
article
OpenAlex
Adivitch Sripusanapan, Chotrawee Piriyakunthorn, Nattayaporn Apaijai, Siriporn C. Chattipakorn et autres
Abstract Background Doxorubicin (DOX) is a widely used chemotherapeutic agent, and cardiotoxicity is one of its well-known side effects, which is mediated by cardiac mitochondrial dysfunction. Ivabradine (IVA), a heart rate reduction drug, exerts benefits in various cardiac diseases as shown in …
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