Leyi Wang

Lipid levels and risk-stratified management gaps of dyslipidemia in China

Long Zhang, X F Liu, Fangfang Fan, M Zhang et autres

BACKGROUND: Dyslipidemia remains a major modifiable contributor to China's cardiovascular disease (CVD) burden, yet large-scale evidence on risk-stratified management gaps is lacking. METHODS: In this nationwide study across 1,785 hospitals in 28 Chinese provinces, 604,250 outpatients with dyslipidemia were enrolled. We analyzed …

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Lipoprotein subfractions in cardiovascular disease risk prediction and therapeutic targeting: Current landscape and future directions

L Zhang, Shuo Zhang, Yangyang Sun, Leyi Wang et autres

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Association Between Neutrophil Percentage‐to‐Albumin Ratio (NPAR) and Risk of Stroke in Patients With Hypertension: A Cohort Study

Leyi Wang, Z K Liu, Nan Zhang, L Zhang et autres

Stroke is a leading cause of disability among hypertensive adults, with notable sex differences in risk and outcomes. Neutrophil percentage-to-albumin ratio (NPAR) is an easily obtainable composite index of systemic inflammation with prognostic value in cardiovascular disease, but its utility for primary …

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Schisandra chinensis lignans and polysaccharides alleviate MASH via ASAH1-mediated regulation of hepatic ceramide homeostasis

Qi Chen, Leyi Wang, Zhihao Zhou, Lin Ying Xie et autres

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ASSOCIATION BETWEEN NEUTROPHIL PERCENTAGE-TO-ALBUMIN RATIO AND RISK OF STROKE IN PATIENTS WITH HYPERTENSION: A COHORT STUDY

Leyi Wang, Zhihao Liu, Nan Zhang, Xu Liu et autres

Objective: Stroke accounts for a great proportion of the global burden of disease and neutrophil percentage-to-albumin ratio (NPAR) has been reported as a critical predictor on the risks and clinical outcomes of cardiovascular diseases (CVDs). This study investigated the predictive value of …

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Lipid Characteristics and Control Gaps in Dyslipidemia Management in China: Findings from a Nationwide Cohort of 604250 Individuals

Long Zhang, Xu Liu, Fangfang Fan, Zhihao Liu et autres

The predictive value of cumulative atherogenic index of plasma (AIP) for cardiovascular outcomes: a prospective community-based cohort study

Zhihao Liu, Long Zhang, Leyi Wang, Kaiyin Li et autres

BACKGROUND: Atherogenic index of plasma (AIP) has been reported as a critical predictor on the risks and clinical outcomes of cardiovascular diseases (CVDs), and we aimed to explore the potential predictive value of cumulative AIP on major adverse cardiac events (MACE), stroke, …

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The regulation of GSH/GPX4-mediated lipid accumulation confirms that schisandra polysaccharides should be valued equally as lignans

Lijuan Xue, Leyi Wang, Yexin Xu, Haoyang Feng et autres

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Feasibility exploration of GSH in the treatment of acute hepatic encephalopathy from the aspects of pharmacokinetics, pharmacodynamics, and mechanism

Kangrui Hu, Yexin Xu, Jiye Fan, Huafang Liu et autres

Our previous study highlighted the therapeutic potential of glutathione (GSH), an intracellular thiol tripeptide ubiquitous in mammalian tissues, in mitigating hepatic and cerebral damage. Building on this premise, we posited the hypothesis that GSH could be a promising candidate for treating acute …

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Inter-leg systolic blood pressure difference has been associated with all-cause and cardiovascular mortality: analysis of NHANES 1999–2004

Geng Shen, Zhihao Liu, Leyi Wang, Jianping Li

BACKGROUND: Inter-leg systolic blood pressure difference (ILSBPD) has emerged as a novel cardiovascular risk factor. This study aims to investigate the predictive value of ILSBPD on all-cause and cardiovascular mortality in general population. METHODS: We combined three cycles (1999-2004) of the National …

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Annuloselectivity of Dibenzoxazepines and Arynes in the Presence of CO 2 : [2+2] vs [2+2+2] Annulation

Kun Zhang, Shiqi Liu, Leyi Wang, Xiangrui Liu et autres

Abstract The annulation of arynes with dibenzo[ b , f ][1,4]oxazepines ( N ‐aryl cyclic imines) in the presence of CO 2 has been studied in comparison with 3,4‐dihydroisoquinolines ( N ‐alkyl cyclic imines). For the reaction with dibenzo[ b , f …

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