Short chain fatty acids potentiate azoles by reprogramming fungal acetyl-CoA metabolism
Christopher McCrory, Sofya Rabinovich, Harshini Chamindri Weerasinghe, Tricia L. Lo et autres
ABSTRACT Pathogens colonise metabolically diverse host environments. How metabolites found in host environments regulate antimicrobial drug susceptibility remains to be fully understood. Here we report on the roles of gut metabolites, short chain fatty acids (SCFAs), in antifungal drug susceptibility of the …
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bioRxiv (Cold Spring Harbor Laboratory)