Jingjing Lou

Remnant Cholesterol Inflammatory Index and Its Association With All‐Cause Mortality Among General Population and Individuals With Cardiovascular–Kidney–Metabolic Syndrome Stages 0–3: Evidence From Two Nationwide Studies

Chen‐Zhang Ou, Zhong-Qiang Liu, Yu‐Jun Xiong, Shiqin Chen et autres

BACKGROUND: Early identification of mortality risk in cardiovascular-kidney-metabolic (CKM) stages 0-3 remains challenging. The remnant cholesterol inflammatory index (RCII) has been associated with adverse outcomes, but its comparative prognostic performance in early CKM stages is unclear. METHODS: We analyzed data from two …

cn (code pays fourni par la source)

Recent implications of FAPI PET in cardiac diseases

Lan Wang, Shixing Huang, Fengling Shan, Jingjing Lou et autres

Abstract Fibroblast activation protein (FAP), highly expressed in activated fibroblasts within injured myocardium, serves as the molecular target for FAP inhibitor (FAPI)‐based imaging. Among developed radiopharmaceuticals, 68 Ga‐FAPI and 18 F‐FAPI demonstrate rapid target‐tissue accumulation and low background signals, yielding superior imaging …

cn (code pays fourni par la source)

Dose-Dependent Cellular Phenotypic Change Induced by 177Lu-Oxodotreotide Treatment in IMR-32 Cells

Shuai Xue, Xiaobei Zheng, Bingbing Pu, Xiao Li et autres

Objectives: Beta-emitting radionuclide therapy, exemplified by 177Lu-Oxodotreotide (Lutathera®), enables targeted treatment of neuroendocrine tumors by delivering β-radiation to tumor cells. However, the dose-dependent molecular mechanisms underlying cellular damage remain insufficiently characterized. This study aimed to investigate the phenotypic changes in IMR-32 human …

cn (code pays fourni par la source)

E-Urea-K-Based PSMA Imaging Served as an Alternative in Assessing Tumor Neovascularization via Targeting CD31

Lan Wang, Shengnan Ren, Jingjing Lou, Shuai Xue et autres

To reveal the natural correlation between prostate-specific membrane antigen (PSMA) imaging and tumor neovascularization in prostate cancer and further explore E-urea-K-based PSMA-targeted (EK-PSMA) imaging as a potential indicator of tumor neovascularization, the 22Rv1 mouse models were established and underwent 99m Tc-HYNIC-ALUG SPECT/CT. …

cn (code pays fourni par la source)

Targeting senescence with radioactive 223Ra/Ba SAzymes enables senolytics-unlocked One‐Two punch strategy to boost anti-tumor immunotherapy

Jiajia Zhang, Shenghong Zhang, Chao Cheng, Chunyan Zhu et autres

cn (code pays fourni par la source)

Application of Static Surface Current Modes in Electromagnetic Scattering Problems

Jingjing Lou, Gaobiao Xiao, Ting Zang

The application of static surface current modes in analyzing electromagnetic scatterings from perfect electrically conducting (PEC) targets is presented in this paper. Static surface current modes are able to solve the low-frequency collapse problem. In addition, static surface current modes are independent …

cn (code pays fourni par la source)

Alpha‐Emitter Radium‐223 Induces STING‐Dependent Pyroptosis to Trigger Robust Antitumor Immunity

Mengdie Yang, Haipeng Liu, Jingjing Lou, Jiajia Zhang et autres

Abstract Radium‐223 (223Ra) is the first‐in‐class alpha‐emitter to mediate tumor eradication, which is commonly thought to kill tumor cells by directly cleaving double‐strand DNA. However, the immunogenic characteristics and cell death modalities triggered by 223Ra remain unclear. Here, it is reported that …

cn (code pays fourni par la source)

Predictors of pregnancy stress and psychological birth trauma in women undergoing vaginal delivery: a cross-sectional study in China

Dongmei Ma, Shiwen Sun, Jialu Qian, Man Wang et autres

BACKGROUND: Psychological birth trauma exhibits a high incidence worldwide, resulting in a wide range of negative impacts on mothers, infants, couples, families and society at large through the maternal-centered ripple effect. However, there is currently limited research on psychological birth trauma in …

cn (code pays fourni par la source)