A Dinh Le

Current Animal Models of Cleft Lip and/or Palate: A Narrative Review

In-won Chang, Shirley Zheng, Zhong Sheng Zheng, A Dinh Le et autres

Cleft lip with or without cleft palate (CL/P) is one of the most common congenital craniofacial anomalies worldwide and presents significant functional, esthetic, and psychosocial challenges. Despite advances in multidisciplinary care and surgical reconstruction, complications such as impaired wound healing, scar formation, …

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Distinct genomic and immunologic tumor evolution in germline TP53-driven breast cancers

Nabamita Boruah, David José Hernández Hoyos, Renyta Moses, Ryan M. Hausler et autres

Pathogenic germline TP53 alterations cause Li-Fraumeni Syndrome (LFS), and breast cancer (BC) is the most common cancer in LFS females. Here, we perform a multimodal analysis, comparing LFS-BC with sporadic premenopausal breast cancer which shows that nearly all LFS-BC undergo biallelic loss …

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Abstract 4695: Distinct genomic remodeling in Li Fraumeni Syndrome breast cancer

Nabamita Boruah, Renyta Moses, Ryan M. Hausler, Heena Desai et autres

Abstract Background: Pathogenic germline variants (PGVs) in TP53 cause Li-Fraumeni Syndrome (LFS), a hereditary multicancer predisposition syndrome. Among females with LFS, breast cancer (BC) is the most prevalent malignancy, affecting 80-90% of carriers, typically at a much earlier age than sporadic cases …

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The State of Medical Education on Criminal Justice Health: A Systematic Review

A Dinh Le, Rose Onyeali, Nicole Mushero

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E-037 What Stroke Patients Post Online About: An Instagram and Twitter Analysis

Avi A. Gajjar, Anupriya Jain, A Dinh Le, M Salem et autres

Introduction Increased social media usage has allowed many individuals and patients to connect and influence their patient population through providing their own opinions and health experiences. Conducting patient feedback surveys serves as a valuable means for obtaining important information about patients’ sense …

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O-051 What matters most to cerebral aneurysm patients: a digital analysis of patients’ perception via social media

Avi A. Gajjar, M Salem, Anupriya Jain, R Davis et autres

Introduction Social media has grown exponentially throughout the 21st century and serves as a way for patients to post about their condition online, as well as for healthcare providers to disseminate information. Intrinsic bias may exist when patients are given surveys by …

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