Yanjun Gao

Glomerular Injury Induced by Daily Exposure to the Low-Frequency Component of Environmental Noise via Endothelin Signaling in Mice

Takumi Kagawa, Dijie Chen, Nobutaka Ohgami, Keming Tong et autres

Epidemiological studies suggest that environmental noise is associated with kidney dysfunction in humans; however, the underlying characteristics, such as frequency, intensity, and duration, remain unclear. Effects of exposure to whole environmental noise generated by electric devices (all frequencies), low-frequency noise (LFN; ≤100 …

jp, cn, us (code pays fourni par la source)

Emerging Inverse Association Between Low Exposure to Vanadium and Kidney Function Impairment: a Cross-Sectional Analysis of Japanese Residents

Yanjun Gao, Takumi Kagawa, Weixin Chen, Akihito Harusato et autres

jp (code pays fourni par la source)

Efficacy and Safety of Peripheral Nerve Blocks After Arthroscopic Shoulder Surgery: A Systematic Review and Network Meta-Analysis

Yanjun Gao, Jinwen Huang, Zhilong Liu, Zhongyuan Hu et autres

Background: Nerve blocks are commonly used for analgesia following shoulder arthroscopy, but the optimal technique remains uncertain. This network meta-analysis (NMA) evaluates the effect of peripheral nerve blocks in adults undergoing shoulder arthroscopy. Methods: We searched databases including PubMed, Embase, Web of …

cn (code pays fourni par la source)

AND-1 is a critical regulator of R-loop dynamics and a target to overcome endocrine resistance

Z. Li, Yihan Peng, Huai-Chin Chiang, Yanjun Gao et autres

R-loops are three-stranded DNA/RNA hybrids that are essential for various cellular pathways. However, when dysregulated, they lead to genomic instability and numerous human diseases. R-loops are tightly regulated, with RNase H1 acting as a key enzyme responsible for resolving DNA/RNA hybrids. Here, …

us (code pays fourni par la source)

Programmed Intermittent Bolus versus Continuous Infusion for Regional Analgesia Following Thoracoscopic Surgery: A Systematic Review and Meta-Analysis

Dongqing Ren, Zhilong Liu, Yanjun Gao, Na Xie et autres

Background: Continuous regional analgesia techniques have emerged as a more effective alternative for postoperative analgesia, but the clinical efficacy of infusion modes in thoracoscopic surgery remains controversial. This systematic review and meta-analysis to compare the efficacy of programmed intermittent bolus infusion (PIBI) …

cn (code pays fourni par la source)

Data from Stabilization of RUNX1 Induced by O-GlcNAcylation Promotes PDGF-BB–Mediated Resistance to CDK4/6 Inhibitors in Breast Cancer

Shuyan Zhou, Yi Zhang, Julie Belmar, Chunyan Hou et autres

Abstract Cyclin-dependent kinases 4 and 6 (CDK4/6) are crucial in regulating cell-cycle progression and cancer development. Targeting CDK4/6 has shown considerable promise in treating various cancers, including breast cancer. Despite significant therapeutic efficacy, resistance to CDK4/6 inhibitors (CDK4/6i), such as palbociclib, remains …

Supplementary Table S1 from Stabilization of RUNX1 Induced by O-GlcNAcylation Promotes PDGF-BB–Mediated Resistance to CDK4/6 Inhibitors in Breast Cancer

Shuyan Zhou, Yi Zhang, Julie Belmar, Chunyan Hou et autres

Primers for qRT-PCR, Chip-PCR and O-GlcNAc mutant sites

Supplementary Table S3 from Stabilization of RUNX1 Induced by O-GlcNAcylation Promotes PDGF-BB–Mediated Resistance to CDK4/6 Inhibitors in Breast Cancer

Shuyan Zhou, Yi Zhang, Julie Belmar, Chunyan Hou et autres

RUNX1 O-GlcNAcylation sites

Supplementary Table S1 from Stabilization of RUNX1 Induced by O-GlcNAcylation Promotes PDGF-BB–Mediated Resistance to CDK4/6 Inhibitors in Breast Cancer

Shuyan Zhou, Yi Zhang, Julie Belmar, Chunyan Hou et autres

Primers for qRT-PCR, Chip-PCR and O-GlcNAc mutant sites

Supplementary Data from Stabilization of RUNX1 Induced by O-GlcNAcylation Promotes PDGF-BB–Mediated Resistance to CDK4/6 Inhibitors in Breast Cancer

Shuyan Zhou, Yi Zhang, Julie Belmar, Chunyan Hou et autres

Supplementary Figures

Stabilization of RUNX1 Induced by O-GlcNAcylation Promotes PDGF-BB–Mediated Resistance to CDK4/6 Inhibitors in Breast Cancer

Shuyan Zhou, Yi Zhang, Julie Belmar, Chunyan Hou et autres

Cyclin-dependent kinases 4 and 6 (CDK4/6) are crucial in regulating cell-cycle progression and cancer development. Targeting CDK4/6 has shown considerable promise in treating various cancers, including breast cancer. Despite significant therapeutic efficacy, resistance to CDK4/6 inhibitors (CDK4/6i), such as palbociclib, remains a …

us (code pays fourni par la source)

Alleviating effect of intranasal zinc on symptoms of allergic rhinitis

Huadong Xu, Keming Tong, Naruhito Iwasaki, Nobutaka Ohgami et autres

Background: There is no information about the clinical implications and kinetics of zinc (Zn) in the nasal cavity, a center of allergic inflammation, and serum in subjects with allergic rhinitis (AR). Objective: Effects of intranasal Zn on symptoms before and after allergen …

cn, jp (code pays fourni par la source)