C. Hawkins

Patterns of hypermutation shape tumorigenesis and immunotherapy response in mismatch-repair-deficient glioma

Nicholas R. Fernandez, Yuan Chang, Nuno Miguel Nunes, Jose Rafael Dimayacyac et autres

ca, us, de, nz, il, gb (code pays fourni par la source)

Disseminated pediatric low-grade glioma and hydrocephalus: a multinational consortium analysis of incidence and mortality

Alexander T Lyons, Joseline Haizel‐Cobbina, Adrian J. Levine, Anthony E. Bishay et autres

OBJECTIVE: Disseminated pediatric low-grade gliomas (DPLGGs) are a rare subtype of an otherwise common tumor, characterized by leptomeningeal dissemination, with microtumors spreading throughout the CNS. The impact of this dissemination on CSF dynamics remains unexplored. The authors describe the occurrence, treatment, and …

us, ca, gb, au, ch, br, pk, hr, jp, il, es, Afrique du Sud (code pays fourni par la source)

Eruptive Acral Nevi Secondary to Treatment With Chemotherapy

Catherine J. Stewart, C. Hawkins

This case report describes an eruption of junctional nevi on the dorsum of both feet.

ca (code pays fourni par la source)

13 The genetic landscape of pediatric low-grade gliomas: Incidence, prognosis and response to therapy - a SickKids pLGG Task Force update

Scott T. Ryall, Michal Zápotocký, Kohei Fukuoka, Ana Guerreiro Stücklin et autres

Molecular characterization of pediatric low-grade glioma (pLGG) over the last decade has identified recurrent alterations, most commonly involving BRAF, and less frequently other pathways including MYB and MYBL1. Many of these molecular markers have been exploited clinically to aid in diagnosis and …

LG-03 * RADIATION THERAPY IS ASSOCIATED WITH INCREASED LATE MORTALITY IN LONG-TERM ADULT SURVIVORS OF CHILDHOOD LOW GRADE GLIOMA: A POPULATION BASED STUDY

Rahul Krishnatry, Nataliya Zhukova, Ana Guerreiro Stücklin, Jason D. Pole et autres

PURPOSE: To uncover clinical risk factors and the impact of radiotherapy on children and adult survivors of childhood low grade glioma (PLGG). METHODS: We collected long-term follow-up information for all PLGG patients diagnosed in all Ontario, Canada from 1985–2012 (n = 1202) …

ca, us (code pays fourni par la source)

EPENDYMOMA

Linda M. Hoffman, Andrew M. Donson, Ichiro Nakachi, Andrea M. Griesinger et autres

EPENDYMOMA

Mariam Salah Zaghloul, AmrM. Mousa, E. Eldebawy, Aamir Amin et autres

Abstract published in Neuro-Oncology, 14(suppl 1): i148-i156, June 2012

fr (code pays fourni par la source)

April 1999--44 year old man with a bleeding intracerebral tumor.

C. Hawkins, Bilbao Jm

A 44 year-old man presented with a three month history of increasing headache and evolving left sided hemiparesis that culminated in an haemorrhage into an intracerebral tumour which was partially resected. Histologic, immunohistochemical, electron microscopic and molecular studies are supportive of a …

ca (code pays fourni par la source)

Evidence for freedom from Johne's disease in cattle and goats in Western Australia

TM ELLIS, RT NORRIS, PAJ MARTIN, RH CASEY et autres

au (code pays fourni par la source)

Ovine Johne's disease: the risk associated with sheep imported into Western Australia

ARB HIGGS, C. Hawkins

OBJECTIVE: To assess the risk of Johne's disease not being detected in sheep imported from New South Wales into Western Australia. DESIGN: A stochastic simulation model. PROCEDURE: The process of importing sheep was broken down into steps and numbers or probabilities assigned …

us, au (code pays fourni par la source)

Carnitine palmitoyl transferase deficiency with an atypical presentation and ultrastructural mitochondrial abnormalities.

Martyn P. Carey, Kelvin Poulton, C. Hawkins, Robert P. Murphy

A case of carnitine palmitoyl transferase deficiency presenting in a 72 year old woman with the clinical picture of ophthalmoplegia plus other muscle weakness is reported. Histological and ultrastructural examination showed the features of a mitochondrial myopathy.