Ileana De Michele

The role of spectrophotometry in the diagnosis of melanoma

Paolo A. Ascierto, Marco Palla, Fabrizio Ayala, Ileana De Michele et autres

BACKGROUND: Spectrophotometry (SPT) could represent a promising technique for the diagnosis of cutaneous melanoma (CM) at earlier stages of the disease. Starting from our experience, we further assessed the role of SPT in CM early detection. METHODS: During a health campaign for …

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Metronomic schedule of temozolomide with conventional dose of cisplatin in metastatic melanoma

Ester Simeone, Antonio Daponte, Gianfranco De Feo, Vincenzo Montesarchio et autres

e20009 Background: Dacarbazine (DTIC) is the standard treatment for metastatic melanoma. Temozolomide (TMZ) is a potentially attractive chemotherapeutic agent for this disease because of the oral route of administration and efficacy similar to that of dacarbazine. Cisplatin is active against melanoma and …

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Human Melanoma Metastases Express Functional CXCR4

Stefania Scala, Paola Giuliano, Paolo A. Ascierto, Caterina Ieranò et autres

PURPOSE: The chemokine receptor CXCR4 was identified as an independent predictor of poor prognosis in primary melanoma. The aim of the study was to investigate the role of CXCR4 in human melanoma metastases. EXPERIMENTAL DESIGN: CXCR4 expression was evaluated in melanoma metastases …

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Adjuvant treatment of malignant melanoma: Where are we?

Paolo A. Ascierto, Stefania Scala, Alessandro Ottaiano, Ester Simeone et autres

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