Ru Feng

The relationship between occupational stigma consciousness and occupational identity among pre-service early childhood education teachers in China: a four-year longitudinal study

Xiaoling Ren, Ru Feng, Zhonglian Yan, Jiaxin Liu et autres

Introduction: For pre-service early childhood education teachers, occupational identity is foundational to career commitment. However, its cultivation is challenged by occupational stigma consciousness. Longitudinal research on their reciprocal relationship remains limited. This study examined this gap over 4 years. Methods: A four-wave …

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[Progress and application of machine learning in sports injury research].

Xinke Li, Chen Yang, Ru Feng, Ke Rong et autres

The research on sports injury has long relied on traditional statistical methods, which often have obvious limitations when dealing with high-dimensional, nonlinear and multi-modal data. With the development of artificial intelligence technology, machine learning provides a new way to solve these complex …

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Urinary microenvironment-degradable nanocapsules for traceable therapy of diabetic nephropathy

Ru Feng, Tao Yue, Xuhui Zhao, Jie Dong et autres

Diabetic nephropathy (DN) is a serious complication of diabetes and a leading cause of end-stage renal disease. Current treatments using anti-inflammatory, antioxidant, and antifibrotic drugs are limited by rapid systemic clearance and poor renal retention. Here, we developed a urine-microenvironment responsive nanocapsule, …

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XPO1 Inhibition enhances sensitivity to platinum-based chemotherapy in germinal-center B-cell-like-DLBCL cells

Qing Su, Xiaolei Wei, Y. Wei, Ru Feng

Platinum-based chemotherapy is considered as salvage therapy to relapsed/refractory diffuse large B-cell lymphoma (DLBCL) patients. However, treatment failure due to drug resistance occurs in some patients, particularly those with Exportin 1 (XPO1) overexpression. This study investigates whether XPO1 inhibition enhances platinum sensitivity …

XPO1 Inhibition enhances sensitivity to platinum-based chemotherapy in germinal-center B-cell-like-DLBCL cells

Qing Su, Xiaolei Wei, Y. Wei, Ru Feng

Platinum-based chemotherapy is considered as salvage therapy to relapsed/refractory diffuse large B-cell lymphoma (DLBCL) patients. However, treatment failure due to drug resistance occurs in some patients, particularly those with Exportin 1 (XPO1) overexpression. This study investigates whether XPO1 inhibition enhances platinum sensitivity …

Effect of stance width during static calibration postures on lower extremity mechanics during running

Yurui Shen, Yuting Zhao, Liduan Wang, Chen Yang et autres

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Smart bioelectronic facemask for non-invasive detection of respiratory infections

Lirong Wang, Ru Feng, Qiang Li, Ruiping Zhang et autres

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Parishin A reduces hepatic encephalopathy via gut microbiota increasing the activity of intestinal EAAT3 to reduce blood ammonia

Jin‐Yue Lu, Hengtong Zuo, Ru Feng, Yilin Chen et autres

Hepatic encephalopathy (HE) is a neuropsychiatric disorder associated with liver dysfunction. Increasing evidence suggests that the gut microbiota plays a critical role in its pathogenesis, yet effective treatment options remain limited. Parishin A (PA), a natural phenolic compound isolated from Gastrodia elata, …

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Outcome and recovery trajectories for intracerebral hemorrhage in adults with primary immune thrombocytopenia

Peng Zhao, Ming Hou, Yi Liu, Ru Feng et autres

Abstract Introduction Intracerebral hemorrhage (ICH) is a rare but devastating complication of immune thrombocytopenia (ITP). Current knowledge is limited in terms of the clinical features and outcome trajectories for ICH in adults with primary ITP. We previously conducted preliminary work to predict …

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CHN1 suppresses B-cell non-Hodgkin lymphoma progression via akt/mTOR pathway

Xiaoya Yun, Weidong Ding, Yifan Liu, Ru Feng et autres

Abstract Introduction B-cell non-Hodgkin lymphoma (B-NHL) is the most prevalent NHL subtype, exhibiting high heterogeneity. Chimerin 1 (CHN1), a rac guanosine triphosphatase activating protein (racGAP), is predominantly expressed in neurons, especially in the cerebral cortex, and plays an important role in axon …

Bioengineered injectable HAMA/GelMA hydrogel encapsulating exosomes loaded lycopene mitigates deoxynivalenol-induced testicular injury via apoptotic pathway modulation

Ru Feng, Ramaiyan Velmurugan, Chunfeng Li, Ying Mu et autres

Deoxynivalenol (Dex), a widespread mycotoxin found in contaminated cereals, induces testicular dysfunction primarily through oxidative stress, inflammation, and activation of apoptotic pathways. Lycopene (Lyc), a natural antioxidant, offers cytoprotective potential but is limited by poor aqueous solubility and instability. To address these …

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Gut Microbiota‐Derived Metabolites Orchestrate Metabolic Reprogramming in Diabetic Cardiomyopathy: Mechanisms and Therapeutic Frontiers

Xinyu Yang, Ru Feng, Meng-Liang Ye, Hui Xu et autres

Diabetic cardiomyopathy (DCM) is a major cardiovascular complication of diabetes mellitus, characterized by myocardial structural and functional abnormalities in the absence of overt coronary artery disease or hypertension. A growing body of evidence implicates the gut microbiota and its metabolites as key …

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