L. M. Souza

A fonética e fonologia aplicadas ao ensino da língua inglesa

Antonia Iara de Oliveira Costa Bastos, Emı́lia Sousa, Felipe dos Santos Ferreira, Francidalva Braga Bezerra et autres

O e-book A Fonética e Fonologia Aplicadas ao Ensino da Língua Inglesa reúne produções acadêmicas de estudantes do curso de Letras: Língua Portuguesa, Língua Inglesa e suas Literaturas, da Universidade Estadual do Maranhão (UEMA), vinculadas à disciplina de Fonética e Fonologia da …

Oncolytic viral therapy with Zika: a promising alternative for glioblastoma treatment

L. M. Souza, Stephanie Zarlotim Jorge, Nicolle Divanenko, Giovanna Soares Correa et autres

Beetroot peel flour: Characterization, betalains profile, in silico ADMET properties and in vitro biological activity

Pedro Paulo Saldanha Coimbra, Adrielli de Carvalho Teixeira, Maria Eduarda Flores Trindade, G. Brito et autres

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A RELAÇÃO ENTRE A FONÉTICA E A ESCRITA: dificuldades de compreensão entre o som e a escrita da língua inglesa

Felipe dos Santos Ferreira, Larissa Silva Nelo Oliveira, L. M. Souza

Este estudo tem como objetivo investigar a relação entre fonética e escrita na aprendizagem da língua inglesa, destacando as dificuldades enfrentadas por falantes do português. A pesquisa, de natureza qualitativa e bibliográfica, analisa como a ausência de determinados sons no português e …

Heterocyclic phytometabolites formononetin and arbutin prevent in vitro oxidative and alkylation-induced mutagenicity

Lizandra Vitória de Souza Santos, Bárbara Verena Dias Galvão, L. M. Souza, Andréia da Silva Fernandes et autres

Phenolic phytometabolites are promising bioactive compounds for management of genomic instability related diseases. Formononetin (FMN) and arbutin (ARB) are found in several plant sources. Our goal was to investigate the safety and efficacy of FMN and ARB using in vitro both standardized …

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Resveratrol attenuates doxorubicin-induced toxicity during in vitro culture of mouse-isolated preantral follicles

Gizele Augusta Lemos da Silva, Alane Pains Oliveira do Monte, Anna Thaylla Venceslau França, Istefani Moreira Mota et autres

Summary The aims of this study were to evaluate the doxorubicin concentration that induces toxic effects on in vitro culture of isolated mouse secondary follicles and to investigate whether resveratrol can inhibit or reduce this toxicity. Secondary follicles were isolated and cultured …

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Cytokine Treatment of Radiation-Induced Hemopoietic Suppression: Results of Interleukin-6 and Granulocyte Colony-Stimulating Factor in a Murine Radiation Model

Myra L. Patchen, Thomas J. MacVittie, Brian D. Solberg, R Fischer et autres

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Treatment of Hairy Cell Leukemia with Granulocyte Colony-Stimulating Factor and Recombinant Consensus Interferon or Recombinant Interferon-Alpha-2b

John A. Glaspy, L. M. Souza, Steven M. Scates, Michael A. Narachi et autres

Patients with hairy cell leukemia and neutropenia (absolute neutrophil count less than 1.5 x 10(9)/L) were treated with recombinant granulocyte colony-stimulating factor (G-CSF) at doses of 3.6 and 7.2 micrograms/kg by daily subcutaneous injection, until normalization of neutrophil counts occurred. Patients then …

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Synergy between G-CSF and WR-2721: Effects on Enhancing Hemopoietic Reconstitution and Increasing Survival Following Exposure to Ionizing Radiation

Myra L. Patchen, Thomas J. MacVittie, L. M. Souza

Impaired response of myelodysplastic marrow progenitors to stimulation with recombinant haemopoietic growth factors.

Shoshana Merchav, Gerard Wagemaker, L. M. Souza, Ilana Tatarsky

The regulation of haemopoiesis in myelodysplastic syndromes (MDS) was evaluated by measuring and comparing the in vitro response of marrow progenitors from 18 MDS patients to stimulation with recombinant haemopoietic growth factors (HGFs), granulocyte-macrophage colony-stimulating factor (GM-CSF), granulocyte CSF (G-CSF) and interleukin-3 …

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Survival enhancement and hemopoietic regeneration following radiation exposure: therapeutic approach using glucan and granulocyte colony-stimulating factor.

ML Patchen, T J MacVittie, B D Solberg, L. M. Souza

C3H/HeN female mice were exposed to wholebody cobalt-60 radiation and administered soluble glucan (5 mg i.v. at 1 h following exposure), recombinant human granulocyte colony-stimulating factor (G-CSF; 2.5 micrograms/day s.c., days 3-12 following exposure), or both agents. Treatments were evaluated for their …

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Hemogram Changes in Lactating Dairy Cows Given Human Recombinant Granulocyte Colony Stimulating Factor (r-MethuG-CSF)

James S. Cullor, N. Hamilton Fairley, Wayne L. Smith, Stephen L Wood et autres

As a prelude to mammary gland challenge experiments, this investigation was implemented to assess the hematologic changes in lactating dairy cattle induced by two dosage regimes of human recombinant colony stimulating factor (Hr-GCSF). This study documents the capability of the human recombinant …

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