Gregory H. Turner

Supplementary Table S5 from Conditional Activation of c-MYC in Distinct Catecholaminergic Cells Drives Development of Neuroblastoma or Somatostatinoma

Tingting Wang, L. Liu, Jie Fang, Hongjian Jin et autres

GSEA results for c-MYC PNET and c-MYC neuroblastoma

Supplementary Table S1 from Conditional Activation of c-MYC in Distinct Catecholaminergic Cells Drives Development of Neuroblastoma or Somatostatinoma

Tingting Wang, L. Liu, Jie Fang, Hongjian Jin et autres

CSTN tumor metadata

Supplementary Table S4 from Conditional Activation of c-MYC in Distinct Catecholaminergic Cells Drives Development of Neuroblastoma or Somatostatinoma

Tingting Wang, L. Liu, Jie Fang, Hongjian Jin et autres

Differentially expressed genes in c-MYC PNET and c-MYC neuroblastoma

Supplementary Table S3 from Conditional Activation of c-MYC in Distinct Catecholaminergic Cells Drives Development of Neuroblastoma or Somatostatinoma

Tingting Wang, L. Liu, Jie Fang, Hongjian Jin et autres

Differentially expressed genes in c-MYC- and MYCN-driven neuroblastomas

Nuclear export as a therapeutic vulnerability in ZFTA-RELA ependymoma

Siri Manasa Ippagunta, Amir Arabzade, Srinidhi Varadharajan, Erik Emanus et autres

BACKGROUND: Ependymoma (EPN) is the third most common pediatric brain tumor with no targeted therapies available to patients. In supratentorial ependymoma, the most frequent driver alteration is a gene fusion between ZFTA and RELA (denoted ZR), leads to constitutive localization of ZR …

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EXTH-74. Nuclear Transport as a Therapeutic Vulnerability in ZFTA-RELA Ependymoma

Siri Manasa Ippagunta, Amir Arabzade, Srinidhi Varadharajan, Erik Emanus et autres

Abstract Ependymoma (EPN) is the third most common pediatric brain tumor with no targeted therapies available to patients. The most frequent driver alteration is a gene fusion between ZFTA and RELA (denoted ZR), which leads to constitutive localization of ZR in the …

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RBM39 degrader invigorates innate immunity to eradicate neuroblastoma despite cancer cell plasticity

Shivendra Vikram Singh, Jie Fang, Hongjian Jin, Lee-Ann Van de Velde et autres

The cellular plasticity of neuroblastoma is defined by a mixture of two major cell states, adrenergic and mesenchymal, which may contribute to therapy resistance. However, how neuroblastoma cells switch cellular states during therapy remains largely unknown, and how to eradicate neuroblastoma regardless …

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Supplementary Table S5 from Conditional Activation of c-MYC in Distinct Catecholaminergic Cells Drives Development of Neuroblastoma or Somatostatinoma

Tingting Wang, L. Liu, Jie Fang, Hongjian Jin et autres

GSEA results for c-MYC PNET and c-MYC neuroblastoma

Supplementary Table S1 from Conditional Activation of c-MYC in Distinct Catecholaminergic Cells Drives Development of Neuroblastoma or Somatostatinoma

Tingting Wang, L. Liu, Jie Fang, Hongjian Jin et autres

CSTN tumor metadata

Data from Conditional Activation of c-MYC in Distinct Catecholaminergic Cells Drives Development of Neuroblastoma or Somatostatinoma

Tingting Wang, L. Liu, Jie Fang, Hongjian Jin et autres

Abstract c-MYC is an important driver of high-risk neuroblastoma. A lack of c-MYC–driven genetically engineered mouse models (GEMM) has hampered the ability to better understand mechanisms of neuroblastoma oncogenesis and to develop effective therapies. In this study, we showed that conditional c-MYC …

Supplementary Table S4 from Conditional Activation of c-MYC in Distinct Catecholaminergic Cells Drives Development of Neuroblastoma or Somatostatinoma

Tingting Wang, L. Liu, Jie Fang, Hongjian Jin et autres

Differentially expressed genes in c-MYC PNET and c-MYC neuroblastoma

Supplementary Data from Conditional Activation of c-MYC in Distinct Catecholaminergic Cells Drives Development of Neuroblastoma or Somatostatinoma

Tingting Wang, L. Liu, Jie Fang, Hongjian Jin et autres

Supplementary Data including 12 figures and table S1