Pu Zhao

Ectopic fat deposition in intestinal wall caused the increase of L cell pyroptosis mainly through local hypoxia

Yimeng Liu, Huihui Wu, Qian Ma, Zhipeng Lu et autres

cn (code pays fourni par la source)

Ameliorative Effects of Urolithin A Against Cadmium-Induced NLRP3-Mediated Pyroptosis and Cognitive Deficits Via Regulating Aryl Hydrocarbon Receptor Signaling

Ying Zhu, Quan Yuan, Junhong Geng, Jieping Hu et autres

Cadmium (Cd) is an important environmental and industrial pollutant that induces neurotoxicity and neurobehavioral disorders in animals. Urolithin A (UA), a gut microbial-derived metabolite from polyphenolic compounds, exhibits potent neuroprotective effects in neurological disorders. Herein, we evaluated the ameliorative impact of UA …

cn (code pays fourni par la source)

Ameliorative effects of Urolithin A against Cadmium-induced NLRP3-mediated pyroptosis and cognitive deficits via regulating Aryl hydrocarbon receptor signaling

Ying Zhu, Quan Yuan, Junhong Geng, Jieping Hu et autres

cn (code pays fourni par la source)

The ameliorative effects of melatonin against BDE-47-induced hippocampal neuronal ferroptosis and cognitive dysfunction through Nrf2-Chaperone-mediated autophagy of ACSL4 degradation

Quan Yuan, Mingwei Wang, Zhaoxiang Zhang, Ruofei Wang et autres

Recent studies demonstrate that lipid peroxidation-induced ferroptosis participates in 2,2',4,4'-tetrabromodiphenyl ether (BDE-47)-evoked neurotoxicity and cognitive dysfunction. Melatonin has been indicated to confer neuroprotection against brain diseases via its potent anti-ferroptotic effects. Therefore, this study aims to explore whether melatonin can mitigate BDE-47-elicited …

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Nitrogen additions and resonant laser energy coupling on diamond deposition using combustion chemical vapor deposition

Pu Zhao, Mengmeng Wang

Lasers feature a potential to steer chemical reactions in combustion flames through resonant excitation of precursors, which changes the species ratio for material synthesis. In this study, diamond deposition using an O2/C2H2/C2H4 flame with NH3 additions was investigated under the CO2 laser …

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GPX4 degradation contributes to fluoride-induced neuronal ferroptosis and cognitive impairment via mtROS-chaperone-mediated autophagy

Pu Zhao, Quan Yuan, Liang Chen, Yilu Ma et autres

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TaskWeaver: A Code-First Agent Framework

Bo Qiao, Liqun Li, Xu Zhang, Shilin He et autres

Large Language Models (LLMs) have shown impressive abilities in natural language understanding and generation, leading to their widespread use in applications such as chatbots and virtual assistants. However, existing LLM frameworks face limitations in handling domain-specific data analytics tasks with rich data …

NLRP3 inflammasome-mediated pyroptosis involvement in cadmium exposure-induced cognitive deficits via the Sirt3-mtROS axis

Dongmei Wang, Yiran Wu, Shihao Sun, Pu Zhao et autres

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BDE-47 flame retardant exposure induces microglial pyroptosis and cognitive deficits by activating the mtROS-NLRP3 axis via Sirt3 downregulation and is salvaged by honokiol

Dongmei Wang, Quan Yuan, Shuwen Liu, Pu Zhao et autres

cn (code pays fourni par la source)