Accès ouvert
2026
article
OpenAlex
Michele Goulart dos Santos, Tainá Guillante, Rafael Felipe de Aguiar, Marcelo Augusto Germani Marinho et autres
Neuroinflammation is a response of the central nervous system to injury, infection, or disease, involving the activation of glial cells and the release of cytokines and reactive species. When sustained or dysregulated, it contributes to the progression of neurological disorders. Quercetin (Que) …
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Accès ouvert
2025
article
OpenAlex
Camila de Oliveira Vian, Rafael Felipe de Aguiar, Marcelo Augusto Germani Marinho, Vitória Pereira Mackmillan et autres
Background/Objectives: Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by motor and cognitive impairments due to dopaminergic neuron loss. The neurotoxin MPTP is commonly used to model PD, as it selectively targets these neurons. Quercetin (QU), a flavonoid with antioxidant properties, …
br
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Accès ouvert
2025
article
OpenAlex
Fernanda Barros de Miranda, Lúcia Emanueli Schimith, Dennis Guilherme da Costa Silva, Camila de Oliveira Vian et autres
Background/Objectives: Epilepsy is a common neurological condition characterized by the occurrence of a seizure. It affects around 50 million individuals worldwide, and despite the large quantity of anti-seizure medications available, 30% of epileptic patients still suffer from seizures. Therefore, it is necessary …
br
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Accès ouvert
2024
article
OpenAlex
Geraldo Bezerra da Silva, Carlos Vasconcelos, João M. Furtado, Rafael Felipe de Aguiar et autres
Tuberculosis (TB) is a chronic infectious and inflammatory disease caused by the bacillus Mycobacterium tuberculosis. Renal TB is the third most common form of extra-pulmonary TB. The disease has shown an increase in incidence in the last decade, and the prison population …
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Accès ouvert
2024
article
OpenAlex
Michele Goulart dos Santos, Diele Bopsin da Luz, Fernanda Barros de Miranda, Rafael Felipe de Aguiar et autres
Neuroinflammation plays a crucial role in the development of various neurological diseases, including neurodegenerative disorders, leading to significant neuronal dysfunction. Current treatments involve the use of non-steroidal anti-inflammatory drugs and steroids; however, they are associated with serious adverse effects, limiting their efficacy. …
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